Attentional Systems in Humans and Monkeys

描述(申请人提供)：最近对人类注意力的研究发现，目标导向的注意力和刺激驱动的注意力重新定向的皮层区域可能存在分歧。刺激驱动的重定向背后的额顶腹侧系统尤其令人感兴趣，因为该系统的损伤似乎会导致空间忽视综合症。由于对这一系统的许多研究都是在猕猴身上进行的，通过了解这种注意力模式是否适用于猕猴，我们对这一额顶叶系统在注意力中的作用的理解将大大增强。我建议进行两个实验，以加深我们对猕猴和人类额顶系统之间的同源性的理解，这些系统蕴含着目标导向控制和刺激驱动的注意力重新定向。我们将通过根据功能、地形组织和位置对两个物种的注意相关区域之间的同源性程度进行分类。这些实验的结果不仅将提高我们对这两个物种注意力系统的理解，还将为未来的功能磁共振成像和注意力的电生理学研究提供指导。

DESCRIPTION (provided by applicant): Recent studies of human attention have uncovered a possible divide in the cortical areas underlying goal-directed attention and those underlying stimulus-driven reorienting of attention. The ventral frontoparietal system underlying stimulus-driven reorienting is of particular interest since it seems that damage to this system results in the syndrome of spatial neglect. Since many studies of this system take place in the macaque, our understanding of this frontoparietal system's role in attention will be greatly enhanced by understanding whether this model of attention generalizes to the macaque. I propose to perform a pair of experiments that will further our understanding of the homology between macaque and human frontoparietal systems underlying goal-directed control and stimulus-driven reorienting of attention. We will do this by classifying the degree of homology between the attention-related areas in both species according to function, topographic organization, and location. The results of these experiments will not only improve our understanding of the.attention system in both species, but will also serve as a guide to future fMRI and electrophysiological investigations of attention.