Nanosynthesis of new metallic restorative materials

描述(由申请人提供)：长期的公共健康问题和环境污染源是目前汞合金牙体填充物的责任。本研究的目的是开发不含汞的新型金属修复材料。第一阶段将演示纳米技术，以生产修复材料，这些材料很容易凝结到牙洞中，而不使用或含有危险化学品。因此，第一阶段将对基本冷凝程序进行评估，并对有前景的修复材料进行表征，以确定可与汞齐相媲美的性能特征。一旦建立了可行的纳米合成和缩合过程，第二阶段将致力于开发临床可接受的原型系统，这些系统将有可能取代汞齐产品。商业应用：新的无汞牙科填充材料将为逐步淘汰汞合金提供激励或必要的过渡，而不会对普通人群和牙医造成成本和临床程序影响。消除牙科实践中的汞还将大大减少全球环境中的汞来源。潜在的商业应用应该非常广泛，因为有一个巨大的牙齿修复市场。由于这些新型合金填充材料使用方便、经久耐用、成本低，与目前市场上的替代材料相比，它们将具有显著的优势。

DESCRIPTION (provided by applicant): Long-term public health concerns and sources of environmental contamination are liabilities of present amalgam-based dental fillings. The purpose of this research is to develop new metallic restorative materials without containing mercury. Phase I will demonstrate the nanotechnology to produce restorative materials which are readily for condensation into the dental cavity without using or containing hazardous chemicals. Consequently, Phase I will evaluate the basic condensation procedure and characterize promising restorative materials in order to establish performance features comparable to amalgam. Once viable nanosynthesis and condensation process are established, Phase II will pursue to the development of clinically acceptable prototype systems that would have the potential of replacing the amalgam products. Commercial Applications: New non-mercury dental filling materials will provide the incentive or an imperative transition for phasing out amalgams without imposing cost and clinical procedure impacts on the general population and dentists. Eliminating mercury from the dental practice would also provide a substantial reduction of the mercury source to the global environment. Potential commercial applications should be very wide, due to a large dental restoration market. Since these new alloy filling materials are easy to apply, durable, and low in cost, they will possess significant advantages over current alternative materials on the market.