Postdoctoral Training in Cancer Genetics

描述（由申请人提供）：这是俄亥俄州州立大学综合癌症中心（OSUCCC）癌症遗传学博士后培训项目的新申请。OSUCCC的30名科学家将联手培养下一代癌症遗传学家，重点是研究和治疗乳腺癌、胃肠癌和造血系统癌的多学科方法。独特的招聘工具将被用来吸引三个有才华的博士后候选人每年的计划。认识到对癌症启动和进展的基本机制的完整理解将需要有效地将知识转化为患者的治疗，培训计划编制了一组平衡的研究人员，他们具有遗传学，细胞信号传导，细胞生物学和肿瘤模型方面的专业知识，并具有浓厚的兴趣和转化研究的良好记录。将基础知识与转化和/或临床研究相结合的承诺将通过为博士后学员提供两名具有不同专业知识的共同导师来实现。初级导师和共同导师将共同为学员提供基础研究和转化研究方面的优势，弥合这两个领域之间的差距。选定的培训教师在三个癌症主题中的每一个都有广泛的正在进行的合作研究。该培训计划将加强这些预先存在的互动，并促进癌症遗传学研究的基本和转化概念的知识和实践交流。学员将参加由学员专门介绍的双周癌症遗传学杂志俱乐部，还将参加几个短期课程和系列研讨会，包括每月一次的癌症遗传学系列讲座。学员将通过该计划进行必要的技能培训，以建立转化癌症研究的独立研究计划。

DESCRIPTION (provided by applicant): This is a new application for a postdoctoral training program in cancer genetics at the Ohio State University Comprehensive Cancer Center (OSUCCC). Thirty scientists at the OSUCCC will join forces to train the next generation of cancer geneticists, with an emphasis on multidisciplinary approaches to the study and treatment of breast, gastro-intestinal and hematopoietic cancers. Unique recruiting tools will be employed to attract three talented postdoctoral candidates each year of the program. Recognizing that a complete understanding of the basic mechanisms of cancer initiation and progression will be required for the efficient translation of knowledge to the treatment of patients, the training program has compiled a balanced group of investigators with expertise in genetics, cell signaling, cell biology and tumor models, and with an intense interest and a proven record in translational research. The commitment to coupling basic knowledge to translational and/or clinical research will be realized by providing postdoctoral trainees with two co-mentors having divergent expertise. Together, the primary mentor and co-mentor will provide trainees with strengths in basic and translational research, bridging the gap between these two areas. The selected training faculty has extensive ongoing collaborative studies in each of the three cancer themes. The training program will enhance these pre-existing interactions and foster intellectual and practical exchange of basic and translational concepts to cancer genetics research. The trainees will participate in a bi-weekly Cancer Genetics Journal Club that is to be presented exclusively by trainees, and will also participate in several short courses and seminar series, including a monthly distinguished lecture series on Cancer Genetics. Trainees will be trained by the program with the necessary skills to establish independent research programs in translational cancer research.