Virology of the Central Nervous System

描述（由申请人提供）：该计划的目的是提供最先进的基础研究博士后培训，旨在了解中枢神经系统病毒感染和疾病的机制。该计划已扩大到包括14个建立和资金雄厚的科学家作为导师，与了解病毒感染的CMS在各种病毒系统的后果的共同利益。该计划的持续承诺是培养高度胜任和独立的研究人员，这些研究人员精通分子和细胞生物学，并拥有足够的技能和知识来开发神经病毒学领域的生产性独立项目。培训方案促进了学员的职业发展，该方案提供：1）在经验丰富的高级科学家的指导下获得全职研究经验; 2）指导使用最先进的设备和技术; 3）知识环境，每周由研究所工作人员或特邀演讲者举办4-5次研讨会，有机会会见来访的科学家和教员，并在神经病毒学和相关领域交流思想; 4）有机会在神经生物学，分子生物学，病毒学和免疫学方面进行正式研究;以及5）研究员每年至少有一次机会向其他研究员和工作人员科学家介绍自己的研究成果，供其评论。受训者来自合格的医学博士，哲学博士、和D.V.M.申请人根据1）以前的学术和研究表现; 2）致力于生物医学研究的证据，特别是CNS的病毒性疾病;和3）以前导师的建议。实习期至少为两年，通常为三年。与公共卫生的相关性：随着HIV/AIDS的持续流行和其他病毒病原体（包括汉坦病毒、西尼罗河病毒、马脑炎病毒、麻疹病毒、脊髓灰质炎病毒和许多其他潜在的传染源）的出现/重新出现，显然将继续强烈需要精通CNS感染的分子病毒学家。因此，该培训方案的整体相关性很高。

DESCRIPTION (provided by applicant): The purpose of this program is to provide state-of-the-art postdoctoral training in basic research directed at understanding the mechanisms of virus infection and disease in the central nervous system. The program has expanded to include fourteen established and well-funded scientists to act as mentors, with the common interest of understanding the consequences of virus infection of the CMS in a wide variety of viral systems. The continued commitment of the program is to train highly competent and independent researchers that are well-versed in molecular and cell biology and that possess skills and knowledge sufficient to develop productive independent programs in the area of neurovirology. Career development of the trainees is facilitated by a training program that provides 1) full-time research experience under the guidance of experienced senior scientists; 2) instruction in the use of state-of-the-art equipment and technologies; 3) an intellectual environment that provides 4-5 seminars per week by the Institute staff or invited speakers, with opportunities to meet with visiting scientists and faculty members and exchange ideas in neurovirology and related fields; 4) opportunity for formal studies in neurobiology, molecular biology, virology, and immunology; and 5) opportunity for fellows to present their own research findings for critique by other fellows and staff scientists at least once a year. Trainees are from a pool of qualified M.D., Ph.D., and D.V.M. applicants on the basis of 1) previous Academic and investigative performance; 2) evidence of commitment to biomedical research, in particular to virus diseases of the CNS; and 3) recommendations from previous mentors. Appointments will be for a minimum of two years, with three years the norm. Relevance to Public Health: With the continuing HIV/AIDS epidemic and the emergence/re-emergence of other viral pathogens including Hantavirus, West Nile, equine encephalitis virus, measles, poliovirus, and a host of other potential infectious agents, it is clear that there will continue to be a strong need for molecular virologists versed in infections of the CNS. Thus, the overall relevance of this training program is high.