Doctoral Training in Bioinformatics

描述(申请人提供)：基因组学正在革命性地研究进化、发育生物学，更广泛地说，是对处于正常和病理状态的细胞的分子生物学的研究。它承诺通过开发基于分子指纹的新诊断学、药物靶标识别和个性化药物来彻底改变医学。这场革命取决于高吞吐量的实验方法、紧密相关的高吞吐量计算方法--机器学习算法、数理统计等-以及允许数千用户之间轻松进行多对多通信的现代信息技术。我们的生物信息学博士项目目前旨在培训两个不同的群体：将成为该领域专业人员的研究人员；即将通过开发创造性实验研究所需的新方法来推动该领域向前发展的研究人员；以及将成为该技术用户的生物医学研究人员。由于计算和实验是紧密结合在一起的，该项目的所有学生除了在计算方法方面进行强化培训外，还必须有实际操作经验。为了认识到这些技术可能对社会结构产生的深远影响，所有学生都被要求学习一门关于基因组学的法律和伦理影响的核心、全学分的课程。

DESCRIPTION (provided by applicant): Genomics is revolutionizing research in evolution, developmental biology and, more generally, in the molecular biology of the cell in normal and pathological states. It promises to revolutionize medicine by the development of new diagnostics based on molecular fingerprints, the identification of drug targets, and individualized medicine. The revolution rests on high throughput experimental methods, closely associated high throughput computational methods--machine learning algorithms, mathematical statistics and the like---and modem information technologies that permit easy many to many communication between thousands of users. Our Ph.D. Program in Bioinformatics is currently directed at training two different groups: researchers who will become professionals in the field; i.e. who will move it forward by the development of new methods required for creative experimental research; and biomedical researchers who will be users of the technologies. Because computation and experiment are tightly coupled, all students in the Program must have hands on experience at the bench in addition to intensive training in computational methods. In recognition of the profound effect these technologies are likely to have on the social fabric, all students are required to take a core, full-credit course on legal and ethical implications of genomics.