Applied Biology and Bioprocess Engineering Training

描述(由申请人提供)： 目的和计划特点 应用生物学和生物技术培训计划的目的是提供一个课程和研究环境，为化学和生物工程、生物化学、细胞和分子生物学的博士前培训人员在生物技术领域的职业生涯做好准备。具体地说，该计划侧重于与生物技术、制药和化学公司的需求相关的领域的研究培训，这些公司目前参与使用生物路线制造产品。学员在分子遗传学、细菌、酵母和真菌发酵、哺乳动物细胞培养、酶技术、生物制品回收和提纯、组合生物催化和化学以及材料科学和生物工程的生物医学应用等领域获得专业知识。 研究生课程包括细胞培养技术(哺乳动物和细菌细胞培养)、蛋白质和酶分离、纯化和固定化、突变和基因表达、蛋白质和核酸化学和生物化学、分离和纯化方法、生物传感器和生物信息学的实验室和课堂教学。与之配套的研讨会课程涉及工业研究和开发活动和高级科学领域，包括重组生物发酵、组织工程、生物产品回收(包括大分子分离)、定点突变技术、代谢调节、酶抑制剂设计以及酶和抗体在有机合成中作为催化剂的应用。国际知名科学家在各种相关学科的讲座进一步丰富了培训计划。研究是在教师导师的监督下在上述各个领域进行的。在实习期间，学生们还会进行工业实习，通常是在旧金山湾区的生物技术公司。 实习生 博士前学生将以不同的背景进入该项目，他们都拥有工程或科学学士学位(一些人拥有硕士学位)，还有一些人以前有过工业经验。他们将根据本科生的学业表现、GRE考试成绩、本科生院校教职员工和伯克利分校导师的推荐来选择。请求为12名受训人员提供支持。参加科室的博士生项目平均年限为5.5年。

DESCRIPTION (provided by applicant): Purpose and Program Characteristics The purpose of the Applied Biology and Biotechnology training program is to provide a curriculum and research environment that prepares trainees in chemical and bioengineering, biological chemistry, cell and molecular biology at the predoctoral level for careers in biotechnology. Specifically, this program focuses on research training in areas relevant to the needs of biotechnology, pharmaceutical and chemical companies currently involved in the manufacture of products using biological routes. Trainees acquire expertise in areas such as molecular genetics, bacterial, yeast and fungal fermentation, mammalian cell culture, enzyme technology, bioproduct recovery and purification, combinatorial biocatalysis and chemistry, and biomedical applications of materials science and bioengineering. The graduate program includes laboratory and classroom instruction in cell culture techniques (mammalian and bacteria cell culture), protein and enzyme isolation, purification and immobilization, mutagenesis and gene expression, protein and nucleic acid chemistry and biochemistry, separation and purification methods, biosensors and bioinformatics. This is supplemented with seminar courses on topics spanning industrial research and development activities and advanced scientific areas, including fermentations involving recombinant organisms, tissue engineering, bioproduct recovery (including macromolecular separations), site-directed mutagenesis techniques, metabolic regulation, enzyme inhibitor design and the application of enzymes and antibodies as catalysts in organic syntheses. Lectures from internationally known scientists in a variety of related disciplines further enrich the training program. Research is conducted in the various areas described above under the supervision of the faculty mentors. Students also undertake an industrial internship during the course of their traineeship, typically at Bay Area biotechnology companies. Trainees Predoctoral students will enter the program with varying backgrounds, all holding Baccalaureate degrees in engineering or science (some with Masters degrees), and some with previous industrial experience. They will be selected on the basis of undergraduate scholastic performance, scores on GRE tests, recommendations from faculty at their undergraduate institutions and from their Berkeley mentors. Support for 12 trainees is requested. The average duration of the doctoral program in the participating departments is 5.5 years.