Clinical Studies of Aggressive Behaviors and Alcoholism

一项双盲研究在精心挑选的56名家庭暴力肇事者中比较了氟西汀和安慰剂的效果，初步结果表明，戒酒和服用氟西汀都会降低肇事者具有攻击性的可能性。结果的最终分析将在大约60名参与者完成研究后进行。希望我们的研究结果将导致对家庭暴力的新的治疗形式。 与NIMH合作进行的一项使用PET成像的研究的初步结果显示，与健康对照组相比，家庭暴力肇事者的5-羟色胺转运蛋白位点数量增加。这一发现为为什么肇事者对与恐惧相关的刺激更加敏感提供了一个可能的解释。

Preliminary results from a double blind study, comparing the effects of fluoxetine with placebo in a carefully selected group of 56 perpetrators of domestic violence, show that both the abstinence from alcohol and the administration of fluoxetine decrease the likelihood that perpetrators will be aggressive. Final analyses of the results will be performed after approximately 60 participants have completed the study. It is hoped that the results from our study will lead to new forms of treatment for domestic violence. Preliminary results of a collaborative study with NIMH using PET imaging show that perpetrators of domestic violence have an increased number of serotonin transporter sites when compared to healthy controls. This finding provides a possible explanation for why perpetrators have an increased sensitivity to fear-related stimuli.