SCORE Program: New Mexico State University--Supplement

描述(由申请人提供)：这是一份为拉斯克鲁塞斯的新墨西哥州立大学(NMSU)的SCORE项目申请补充资金的申请。NMSU的一个目标是扩大该机构的研究，让希望从事生物医学科学学科职业的少数民族学生参与其中。拟议的SCORE计划的目标是：(1)在未来四年内，将75%的常规SCORE子项目的研究人员过渡到竞争NIH的R01资金。(2)为了在今后四年内提高定期计分分项目所有研究人员在第二轮资助中的发表记录，每年至少增加33%的研究手稿发表在同行评议的推荐性期刊上。(3)通过开发其核心研究设施，显著提高新墨西哥州立大学进行生物医学相关研究的能力。(4)提高NMSU自我评估、评估和监督SCORE计划的能力，以达到机构自学、计划审查、支持更多计划任务和内部研究管理改进的目的。本申请包含7个研究子项目和7个试验子项目的研究建议。建议研究的具体领域包括：共生真菌的功能基因组学；癌症转移；DNA中的电子传导性和光致电荷转移；非血红素氧化酶的铁的无机化学模型(IV/V/VI)；共生菌的致病机制；作为肥胖决定因素的内分泌机制；布尼亚病毒科病毒复制；婴儿及其母亲的激素、行为和认知同步性；更年期指标的相关研究；病原体和病毒的实时检测和识别；产生抗氧化色素的花青素生物合成途径；作为对遗传态度的相关性的感知遗传史和实际种族史之间的关系(ELSI研究)；以及植物盐胁迫防御的转录分析。

DESCRIPTION (provided by applicant): This is an application for supplemental funding for a SCORE Program at New Mexico State University (NMSU) at Las Cruces. A goal of NMSU is to expand research at the institution for participation by ethnic minority students who desire to pursue careers in the biomedical science disciplines. The proposed SCORE Program has as its goals: (1) To transition, within the next four years, 75% of the investigators of regular SCORE subprojects to competition for R01 funding from NIH. (2) To enhance within the next four years, the publication records of all investigators of regular SCORE subprojects, who are in their second cycle of funding, to a minimum of 33% more research manuscripts per year in peer-reviewed, refereed journals. (3) To significantly improve the capabilities of New Mexico State University to conduct biomedically relevant research through development of its core research facilities. (4) To improve the capacity of NMSU to self-evaluate, assess, and monitor the SCORE Program for the purpose of institutional self-study, program review, support of MORE Program missions, and internal improvement of research management. This application contains research proposals for 7 research subprojects and 7 pilot subprojects. Specific areas proposed for investigation include: functional genomics of symbiotic fungi; cancerous metastases; electronic conductivity and photoinduced charge transfers in DNA; inorganic chemistry models of iron (IV/V/VI) for non-heme oxidases; mechanisms of pathogenesis among symbiotic bacteria; endocrine mechanisms as determinants of obesity; Bunyaviridae virus replication; hormonal, behavioral, and cognitive synchrony in infants and their mothers; correlative studies of indices of menopause; detection and identification of pathogenic bacteria and viruses in real-time; anthocyanin biosynthetic pathways that produce anti-oxidant pigments; relationships between perceived genetic histories and actual ethnic histories as correlates of attitudes toward genetic investigations (ELSI study); and transcriptional analyses of salt-stress defenses in plants.