Nutrional Epidemiology of Cancer

描述(由申请人提供)：此教育计划是在NCI培训科的鼓励和建议下提交的。通过扩大教育和培训项目来推进营养研究，特别是与营养和癌症相关的项目，是国家癌症研究所癌症预防部门营养科学研究组的高度优先事项。这项申请符合R25T机制的指导方针，包括提供持续的领导、专职的教员时间、明确的专业课程、跨学科的研究环境，以及每个计划参与者超过一名导师。这一机制特别合适，因为它适应了这个以营养学和流行病学为基础的项目的特殊跨学科但又有重点的需求。该项目由Meir Stampfer博士领导，Walter Willett博士担任联合首席调查员，Edward Giovannucci博士担任教育主任。 拟议中的计划还有丰富的其他资源可供借鉴。哈佛大学公共卫生学院流行病学系长期以来一直是公认的流行病学方法和癌症流行病学教学培训中心。营养部将相当大的精力集中在营养流行病学上。这一教育计划还利用了达纳-法伯/哈佛癌症中心(DF/HCC)内的各种研究机会，该中心是一个矩阵癌症中心，代表着七个哈佛附属机构的癌症研究。这项工作包括饮食和癌症领域的重大发展，例如建立了三个由250,000多名男性和女性组成的大型队列，并对饮食进行了长达25年的重复测量。该计划的参与者还将有机会熟悉流行病学、癌症病因学和预防方面的其他方面，这些方面超出了培训补助金的重点。通过拟议的培训拨款，我们计划将已经到位的各种要素结合在一起，并创建新的要素，以建立一个协调一致的、专注于癌症营养流行病学的跨学科计划。拟议的癌症营养流行病学培训赠款将提供一个独特的利基市场，它将与其他培训赠款相辅相成，协同增效，以健全的生物学为基础，为癌症预防和控制创造强有力的环境。

DESCRIPTION (provided by applicant): This education program is being submitted with the encouragement and advice of the NCI Training Branch. Advancing nutrition research through expanded education and training programs, especially those related to nutrition and cancer, is a high priority of the Nutritional Science Research Group of the Division of Cancer Prevention at the National Cancer Institute. This application meets the guidelines for the R25T mechanism, including the provision of sustained leadership, dedicated faculty time, a well-defined specialized curriculum, interdisciplinary research environments, and more than one mentor per program participant. This mechanism is particularly appropriate because it is adaptable to the special interdisciplinary, yet focused, needs of this program, which is based on the interface of nutrition and epidemiology. This program is led by Dr. Meir Stampfer, with Dr. Walter Willett as co-Principal Investigator and Dr. Edward Giovannucci as Education Director. The proposed program has a wealth of other resources upon which to draw. The Department of Epidemiology at Harvard School of Public Health has long been a recognized center for didactic training in epidemiologic methods and cancer epidemiology in general. The Department of Nutrition has focused considerable energy in nutritional epidemiology. This educational program also draws on diverse research opportunities within the Dana-Farber/Harvard Cancer Center (DF/HCC), a matrix cancer center representing cancer research across seven Harvard-affiliated institutions. This work has included major developments in the area of diet and cancer such as the creation of three large cohorts comprising over 250,000 men and women with repeated measures of diet followed for as long as 25 years. Participants in this program will also have the opportunity to gain familiarity with other aspects of the broad areas of epidemiology and cancer etiology and prevention that extend beyond the focus of the training grant. Through the proposed training grant, we plan to bring together the various elements already in place, and create new elements to build a coherent and focused interdisciplinary program in nutritional epidemiology of cancer. The proposed training grant in Nutritional Epidemiology of Cancer will provide a unique niche, and it will be complementary, and synergistic, with the other training grants to foster a strong environment for cancer prevention and control, based on sound biology.