Functional suicide of selected dendritic cells by cytochrome c: an in vivo model lacking cross-presentation

某些白细胞（树突状细胞）激活免疫系统，尤其是T细胞。这些细胞的感染会引起杀伤T细胞的反应。然而，并不是所有的感染都会感染树突状细胞。在这种情况下，感染性物质被树突状细胞吞噬并转移到细胞内的特定区域。这个过程被称为交叉表现，它在各种疾病中有多重要仍然没有定论。我们现在有了一个模型通过消除这些交叉呈递细胞来进行测试。

Certain white blood cells (dendritic cells) activate the immune system, especially its T cells. Infection of such cells elicits killer T cell responses. However not all infections infect dendritic cells. In such cases, the infectious material is eaten by dendritic cells and moved to certain areas within the cell. This process is called cross-presentation and how important it is during various diseases remains moot. We now have a model of testing this by eliminating these cross-presenting cells.