Internet Monitoring Of Prescription Drug Abuse

描述（由申请人提供）：本申请拟开发药物风险互联网监测器（PRISM），这是一种创新方法，用于对表明阿片类药物转移/滥用的指标进行上市后监测。这种监测可能会产生新出现的滥用流行病（如奥施康定流行病）的领先指标。公共卫生相关性包括提供可靠和及时的数据，使卫生，执法，行业和社区领导人采取措施，以限制与药物滥用流行病相关的潜在损害。PRISM将自动跟踪和分类特定药品滥用者的互联网“聊天”。具体而言，在第一阶段，一个专家咨询小组将帮助为PRISM指定有用的数据和报告格式，并帮助评估第一阶段的结果。将建立一个系统的、合理的方法来检测和包括/排除要监测的网站。同样在第一阶段，将修改各种内容分析软件程序，以自动检测、跟踪和分类在可访问的留言板上发现的关于阿片类药物的互联网滥用者之间的信息。第一阶段将对PRISM的信度和内部效度进行可行性检验。第二阶段将开发PRISM的完整原型，并证明其可靠性和内部和外部有效性。

DESCRIPTION (provided by applicant): This application proposes to develop the Pharmaceutical Risk Internet Surveillance Monitor (PRISM), an innovative approach to postmarketing surveillance of indicators suggesting diversion/abuse of opioid pharmaceutical agents. Such surveillance may produce leading indicators of an emerging epidemic of abuse (such as the OxyContin epidemic). Public health relevance includes providing reliable and timely data to allow health, law enforcement, industry, and community leaders take steps to limit potential damage associated with an epidemic of pharmaceutical drug abuse. PRISM will automatically track and classify Internet "chatter" by abusers of particular pharmaceutical products. Specifically, in Phase I, an expert advisory group will help specify useful data and report formats for PRISM as well as help evaluate Phase I findings. A systematic, justified methodology will be created for detecting and including/excluding websites to be monitored. Also in Phase I, various content analysis software programs will be modified to automatically detect, track and classify Internet abuser-to-abuser messages about opioid Pharmaceuticals found on publically accessible message boards. A feasibility test of the reliability and internal validity of PRISM will be conducted in Phase I. Phase II will see development of a full prototype of PRISM and demonstration of its reliability and internal and external validity.