INBRE: URI: CENTRALIZED RES CORE FACILITY

描述(由申请人提供)：这个建议的罗德岛卓越生物医学研究网络(RI-INBRE)旨在为博士学位授予和国际扶轮的学士学位机构的研究能力建设提供持续支持，这些机构以前曾得到生物医学研究基础设施网络(BRIN)奖的支持。该提案有四个核心目标：1)在罗德岛州建立一个富有成效的、合作的分子毒理学研究计划；2)为生物医学科学的职业培养有前途的本科生和研究生；3)维护和提供对最先进的生物医学核心研究设施的包容性访问；以及4)建立一个有效的外展计划，以招收代表性不足的科学家和学生。这些目标的实现将由该网络的六个参与机构协作实现。网络活动将通过所需的五个核心进行协调。该方案的总体指导和管理以及初级调查人员的培训和指导由行政核心负责。生物信息学核心将在数据挖掘、数据处理和分子建模需求方面协助研究人员。将通过集中化的 研究机构核心。外联核心将负责招聘、培训和指导属于任职人数不足群体的学生和教职员工。该核心中心的工作人员还将组织研讨会和讲习班，讨论网络参与者共同感兴趣的问题。这四个核心加在一起将有助于提高研究核心的绩效，这是国际扶轮研究所的主要重点活动。对本科生和研究生干部进行研究工具和方法培训将是这项活动的一项重要成果。预计RI-INBRE和RIBRIN一样，将进一步提高国家进行生物医学研究的能力，处于职业生涯早期的网络调查人员将能够更好地为他们的个人或合作项目争取校外研究资金。

DESCRIPTION (provided by applicant): This proposed Rhode Island IDeA Network of Biomedical Research Excellence (RI-INBRE) is designed to provide continuing support for research capacity building both at the doctoral degree granting and at the baccalaureate institutions in RI that have been previously supported by the Biomedical Research Infrastructure Network (BRIN) award. The proposal has four central aims: 1) To build a productive, collaborative research program in molecular toxicology in the state of Rhode Island; 2) To train promising undergraduate and graduate students for careers in the biomedical sciences; 3) To maintain, and provide inclusive access to a state-of-the-art biomedical core research facility; and 4) To establish an effective outreach program for recruiting underrepresented scientists and students. Implementation of these goals will be achieved collaboratively by the six participating institutions in the Network. The Network activities will be coordinated through the five required Cores. The responsibility for overall direction and management of the program, as well as training and mentoring of junior investigators, rests with the Administrative Core. The Bioinformatics Core will assist the investigators in data mining, data processing, and molecular modeling needs. Access to a sophisticated analytical instrumentation will be made available through the Centralized Research Facility Core. Recruitment, training, and mentoring of students and faculty belonging to the Under represented populations will be carried out by the Outreach Core. The staff of this Core will also organize seminars and workshops on topics of mutual interest to the Network participants. Together these four Cores will serve to improve the performance of the Research Core which is the main focused activity of the RI-INBRE. Training a cadre of undergraduate and graduate students in research instrumentation and methodology will be an important outcome of this activity. It is anticipated that the RI-INBRE, like RIBRIN, will further improve the State's capacity to do biomedical research and that the Network investigators, who are at the early stages of their careers, will be better able to compete for extramural research funds for their individual or collaborative projects.