Environmental Health Sciences at Florida International

总体描述（由申请人提供）： 该提案旨在建立一个环境健康研究项目 佛罗里达国际大学是一所少数民族服务机构， 通过一个机制。合作机构将是大学 迈阿密，拥有NIEHS海洋和淡水生物医学科学中心。 一个双重的方法，包括教师的发展和基础设施 发展，将被使用。UM中心围绕着两个主要的 研究主题：海洋毒素和饮食风险和海洋模式系统 人类疾病。该计划将侧重于海洋毒素成分。这 这一主题属于NIEHS赞助的研究范围， 迈阿密大学在海洋毒素研究方面有着良好的记录。这 该计划将是来自两个国家的七名教师之间的合作努力 佛罗里达国际大学的四个系和 迈阿密大学三个不同系的学生。行政和 规划核心小组将为规划署提供行政和文书支援 调查人员在金融情报室，并将协调活动与UM。除了 一名行政助理，负责监督日常运作， 将由三个委员会组成，指导和监督 计划：内部咨询委员会，执行委员会和 外部咨询委员会。项目评估将通过 一个独立的评价者。 海洋毒素主题包括毒素研究和试验项目 毒素的生物合成、药理学和分子建模以及检测 有毒微生物的生物合成途径的表达， 环境条件。为了支持这些研究和试点项目， 培养产毒素微生物的设施核心将是 确立了习这个核心将提供源材料，如文化， 纯化的毒素、DNA、RNA和标记的毒素和抗体。 该计划的主要目标是建立外部资助， 佛罗里达环境健康科学独立研究项目 国际大学，并吸引少数民族学生在 环境健康科学这些将是基准， 方案将进行评估。

OVERALL DESCRIPTION (provided by applicant): This proposal seeks to establish a research program in environmental health sciences at Florida International University, a minority serving institution, via the ARCH mechanism. The partner institution will be the University of Miami, which hosts an NIEHS Marine and Freshwater Biomedical Sciences Center. A twofold approach, including faculty development and infrastructure development, will be used. The UM Center revolves around two principal research themes: Marine Toxins and Dietary Risk and Marine Model Systems of Human Disease. This program will focus on the Marine Toxin component. This theme is within the scope of NIEHS-sponsored research, and scientists at the University of Miami have an established record in marine toxin research. This program will be a collaborative effort between seven faculty from two departments at Florida International University and four faculty at the University of Miami from three different departments. The Administrative and Planning Core will provide administrative and clerical support to ARCH investigators at FIU and will coordinate activities with UM. In addition to an administrative assistant who will oversee day-to-day operation, this core will be composed of three committees to direct and oversee the progress of the program: the Internal Advisory Committee, the Executive Committee, and the External Advisory Committee. Program evaluation will be provided through this core from an independent evaluator. The marine toxin theme encompasses research and pilot projects on toxin biosynthesis, pharmacology, and molecular modeling of toxins and the detection of toxic microorganisms, expression of biosynthetic pathways, and correlation with environmental conditions. To support these research and pilot projects, a facility core for the culture of toxin-producing microorganisms will be established. This core will provide source materials such as cultures, purified toxin, DNA, RNA, and labeled toxins and antibodies. The principal goal of the ARCH program is to establish externally funded, independent research programs in environmental health sciences at Florida International University and to attract minority students to careers in environmental health sciences. These will be the benchmarks by which the program will be evaluated.