CHARACTERIZATION OF THE CONSEQUENCES OF LETHAL YELLOW SYNDROME

描述（由申请人提供）：SD BRIN（由Vermillion的南达科他州大学医学院（SD）赞助）是IDeA生物医学研究卓越网络（INBRE）的南达科他州组成部分。INBRE第二阶段的应用程序是从SD BRIN第一阶段的经验教训和变化中发展而来的。虽然第二阶段的两个主要目标基本上与第一阶段相同，但已稍作修改和澄清，以便更准确地反映网络为第二阶段规划的方向。SD BRIN的愿景是在南达科他州进一步发展一个强大的合作网络，通过跨学科的方法来研究细胞生长的控制，特别强调蛋白质组学和基因组学，提高基本的生物医学研究能力。因此，SD BRIN二期的目标是：1)发展SD在细胞生长控制领域的研究能力，特别强调蛋白质组学和基因组学：a)通过指导主要研究密集型机构的初级教员，提高蛋白质组学和基因组学的研究能力和研究人员的临界数量；b)维护蛋白质组学和基因组学核心设施（配备专业人员），供整个SD的研究人员使用；c)提供更多的研究生培训机会。2)通过以下方式开发南达科他州机构生物医学科学和生物信息学本科和研究生课程的人力资源：A)为参与机构的初级研究人员和教师提供研究支持和指导；b)为以本科生为主的院校的学生提供了解前沿科学研究的机会；c)向本科生介绍生物医学科学和生物信息学的研究生课程和未来职业；d)提高部落学院的科学和研究能力，为进一步接受科学和研究的教育和职业提供机会。

DESCRIPTION (provided by applicant): SD BRIN (sponsored by the University of South Dakota School of Medicine in Vermillion, (SD) is the South Dakota component of the IDeA Networks of Biomedical Research Excellence (INBRE). This application for Phase II of INBRE has evolved from lessons learned and changes made during Phase I of SD BRIN. While the two main goals for Phase II remain essentially the same as in Phase I, they have been slightly modified and clarified to more accurately reflect the directions planned by the Network for Phase II. The vision of SD BRIN is to further develop a strong collaborative Network within South Dakota to enhance basic biomedical research capabilities via an interdisciplinary approach to research in the control of cell growth with special emphasis on proteomics and genomics. Therefore, the goals of Phase II of SD BRIN are to: 1) Develop SD research capacity in the area of control of cell growth with special emphasis on proteomics and genomics by: a) enhancing research capacity and critical mass of investigators in proteomics and genomics by mentoring junior faculty members at lead research intensive institution, b) maintaining proteomics and genomics core facilities (with professional staff) which can be used by investigators throughout SD, and c) providing increased opportunities for graduate training. 2) Develop human resources for undergraduate programs and graduate programs in the biomedical sciences and bioinformatics at South Dakota institutions by: a) providing research support and mentoring for junior investigators and faculty from participating institutions, b) providing opportunities for, and understanding of, cutting-edge scientific research for students at predominantly undergraduate institutions, c) introducing undergraduates to graduate programs and future careers in biomedical sciences and bioinformatics, and d) enhancing science and research capabilities at tribal colleges to provide opportunities for further education and careers in science and research.