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中文摘要
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描述(由申请人提供):从事临床研究的医生数量的下降引起了全国对公共卫生保健迫在眉睫的危机的关注。虽然许多医学领域都受到影响,但精神病学的问题尤其严重,预计短缺促使医学研究所最近对这一问题进行了分析。具有讽刺意味的是,当遗传学和神经科学领域的发现对基础行为科学产生前所未有的影响时,从事以患者为导向的研究事业的精神科医生却出现了短缺。将这些基础科学见解转化为患者护理领域的发现,对于提高我们对严重精神疾病的理解和治疗至关重要。目前的R25申请旨在通过几个具体目标来解决当前心理健康研究教育的危机,包括1)在临床住院医师培训(PGY I和II)的早期形成阶段为医生提供一个以患者为导向的强化指导研究培训(IMPORT)计划,2)在后期住院医师培训(PGY III和IV)中通过持续的纵向研究培训来建立这种早期接触。3)促进项目学员获得住院后(PGY V)研究培训奖学金的机会。4)对这些经验进行提炼和优化,为全国精神病学住院医师以患者为导向的研究培训提供一个全国性的模式。来自R25的资金,加上耶鲁大学的机构资源,每年将允许总共多达4名精神科住院医生接受这种专门的纵向研究培训经验。如果成功,该项目将通过增加对高技能的年轻临床精神病学调查骨干的识别、招募和保留,直接使国家受益;间接地,作为全国其他住院医师培训项目的模板。
英文摘要
DESCRIPTION (provided by applicant): Declines in the numbers of physicians pursuing careers in clinical research have raised national concerns about an impending crisis in public health care. While numerous medical fields are affected, the problem in psychiatry is particularly acute, with projected shortages prompting a recent analysis of the problem by the Institute of Medicine. Ironically, shortages of psychiatrists pursing patient-oriented research careers occur at a time when discoveries in the fields of genetics and neuroscience are having an unprecedented impact on the basic behavioral sciences. Translating such basic science insights into discoveries in the patient-care realm will be crucial for improving our understanding and treatment of severe mental illness. The current R25 application is intended to address the current crisis in mental health research education through several specific aims, including 1) to provide a program of Intensive Mentored Patient-Oriented Research Training (IMPORT) for physicians at their earliest, formative stages of clinical residency training (PGY I & II), 2) to build upon this early exposure through continued longitudinal research training in later residency years (PGY III & IV), 3) to facilitate connections of program trainees to post-residency (PGY V) research training fellowship opportunities, and 4) to refine and optimize these experiences so as to provide a national model for training psychiatry residents across the country in patient-oriented research. Funding from the R25, in conjunction with institutional resources at Yale, will allow a total of up to 4 psychiatric residents per year to receive such specialized longitudinal research training experiences. If successful, the program will benefit the country directly, through the increased identification, recruitment and retention of a highly skilled cadre of young clinical psychiatric investigators, and indirectly, as a template for other residency training programs across the country.
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Assessing Glutamate Homeostasis in Cocaine Addiction Using 7T 1H-MRS
  • 批准号:
    9226608
  • 项目类别:
  • 资助金额:
    $25.13万
  • 财政年份:
    2017
  • 负责人:
    ROBERT T MALISON
  • 依托单位:
Imaging Synaptic Density in the Cocaine-Addicted Brain In Vivo using 11C UCB J PET
  • 批准号:
    9335542
  • 项目类别:
  • 资助金额:
    $20.94万
  • 财政年份:
    2017
  • 负责人:
    ROBERT T MALISON
  • 依托单位:
Glutamate-Glutamine Cycling (Vcyc) in Cocaine Abstinence using 13C-MRS
  • 批准号:
    8861373
  • 项目类别:
  • 资助金额:
    $45.92万
  • 财政年份:
    2015
  • 负责人:
    ROBERT T MALISON
  • 依托单位:
Clinical and Educational Core
  • 批准号:
    7797222
  • 项目类别:
  • 资助金额:
    $18.8万
  • 财政年份:
    2010
  • 负责人:
    ROBERT T MALISON
  • 依托单位:
海外基金