Genetics and genomics of breast and ovarian cancer

我们对乳腺癌和卵巢癌相关基因的数量和性质的了解是有限的。为了快速确定关键的乳腺癌和卵巢癌致癌基因，我的实验室使用了一种综合基因组学方法，将来自几个基因组范围平台的信息结合在一起。支持我们大部分工作的一个关键倡议是LifePool，这是一个独特的队列，由10万名维多利亚时代女性参加BreastScreen，将支持一系列乳腺癌研究。

Our knowledge of the number and nature of the genes involved in breast and ovarian cancer is limited. To rapidly define the critical breast and ovarian cancer-causing genes my laboratory uses an integrative genomics approach whereby information from several genome-wide platforms are combined. A key initiative that will underpin much of our work is Lifepool, which is a unique cohort of 100,000 Victorian women attending BreastScreen that will support a range of research into breast cancer.