Identification of genes in involved in the predisposition, initiation and progression of breast and ovarian cancer

鉴定参与乳腺癌和卵巢癌的易感性、发生和进展的基因

• 批准号: nhmrc : 1041975
• 负责人: Prof Ian Campbell
• 金额: $ 60.61万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/identification-genes-involved-ovarian-cancer/111423
• 关键词: Identification; genes; involved; predisposition; initiation

Our knowledge of the number and nature of the genes involved in breast and ovarian cancer is limited. To rapidly define the critical breast and ovarian cancer-causing genes my laboratory uses an integrative genomics approach whereby information from several genome-wide platforms are combined. A key initiative that will underpin much of our work is Lifepool, which is a unique cohort of 100,000 Victorian women attending BreastScreen that will support a range of research into breast cancer.

我们对乳腺癌和卵巢癌相关基因的数量和性质的了解是有限的。为了快速确定乳腺癌和卵巢癌的关键致病基因，我的实验室采用了整合基因组学方法，将来自多个全基因组平台的信息结合起来。支持我们大部分工作的一个关键举措是Lifepool，这是一个由10万名维多利亚州女性参加BreastScreen的独特队列，将支持一系列乳腺癌研究。