High resolution genome-wide SNP analysis of genetic alterations in early ovarian neoplasms

早期卵巢肿瘤遗传改变的高分辨率全基因组 SNP 分析

• 批准号: nhmrc : 628630
• 负责人: Prof Ian Campbell
• 金额: $ 39.14万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/high-resolution-genome-ovarian-neoplasms/78508
• 关键词: resolution; genome; wide; SNP; analysis

Ovarian cancer is the 5th leading cause of cancer death in women. For such a significant disease, remarkably little is know about its origins and this has limited progress in developing more effective diagnostic markers. We will undertake cutting edge genome-wide analysis of pre-invasive ovarian tumours to identify genetic markers relevant to malignancy. This work will significantly expand our understanding of how ovarian cancers develops.

卵巢癌是妇女癌症死亡的第五大原因。对于如此严重的疾病，人们对其起源知之甚少，这限制了开发更有效的诊断标记物的进展。我们将对侵袭前卵巢肿瘤进行最先进的全基因组分析，以确定与恶性肿瘤相关的遗传标记。这项工作将大大扩展我们对卵巢癌如何发展的理解。