Genetics of Stress Responsiveness

对压力的慢性或极端反应可能导致病理状况，如长期焦虑状态、抑郁和恐慌症。与压力相关的疾病也会导致其他主要的健康问题，如心脏病和免疫系统紊乱。这些疾病状态包括我们这个时代的一些主要医学问题。我们的建议是确定可能参与应激反应的基因，以进一步了解和治疗应激相关疾病。

Chronic or extreme reactions to stress can lead to pathological conditions such as long term anxiety states, depression and panic disorders. Stress related disease also contributes to other major health problems such as heart disease and disorders of the immune system. These disease states include some of the major medical problems of our times. This proposal is to define genes which may be involved in stress responsiveness, to further understand and treat stress related disease.