Hemotologic and Oncologic Diseases of Childhood

描述（由申请人提供）： 我们提议提供机构培训补助金，以培训医生/科学家，他们将有助于改善血液病和恶性肿瘤儿童的诊断、治疗和预防战略。研究员将在爱荷华州儿童医院和罗伊J和露西尔A。卡佛医学院。爱荷华州大学是一个学术医疗中心的所在地，该中心提供全方位的医疗保健，包括为主要是农村家庭的大地理区域提供三级服务。一个小的，快速增长的，少数民族人口也生活和工作在我们的集水区，并在我们的机构接受照顾。我们的农村环境提供了独特的机会，既培训儿科专科医生对血液和恶性疾病困扰这些儿童和招募这些儿童在临床试验。我们提出以下目标：1.扩大受训人员从事学术事业的机会，重点是儿童血液病和恶性疾病。爱荷华州儿科系拥有经认可的ACGME血液学/肿瘤学奖学金计划，并在招募高素质的儿科医生方面建立了良好的记录，这些儿科医生随后将从事学术医学。在这个应用程序中，我们提出了一个机构培训计划，专注于血液或恶性疾病儿童的转化和临床研究。我们部门目前有一个新生儿生物学NICHD培训补助金和儿科心脏病学NHLBI培训补助金，从而提供重要的培训支持，包括一个既定的午餐讨论系列，其中所有儿科专科研究员参加，并专门在爱荷华州开发的独特的奖学金评估计划。通过这种方式，儿科教师的整个爱荷华州部门将与内科，精神病学，神经病学，解剖学和细胞生物学，微生物学，生理学，麻醉学，放射学，放射生物学和外科经验丰富的导师一起工作，提供指导团队，提供翻译或临床研究的平衡培训计划，重点是儿童的血液学或肿瘤学疾病。公共卫生学院的教师参加K-30计划以及我们的正式评估计划。2.为学员提供获得转化医学或临床医学硕士学位或非学位认证的机会。每个研究员的核心课程将集中在提供临床研究硕士学位的爱荷华州大学K-30课程或我们独特的爱荷华州大学转化研究研究生课程。我们在基础医学科学方面拥有公认的专业知识，在我们建议的指导团队中，我们在临床研究方面的专业知识也在不断增长。这些优势将共同构成我们在转化或临床研究中建立培训计划的基础。因此，除了认证或以病人为导向的研究硕士学位，每个研究员将制定一个单独的研究计划，有足够的初步数据，提交一个K-23奖在奖学金完成。3.招募和培训妇女，使其事业成功，从而使患有血液学和肿瘤学疾病的儿童受益。进入医学界的妇女人数正在稳步增加。这一点在儿科住院医师项目中表现得最为明显。不幸的是，在学术儿科和儿科专科，如儿科血液学/肿瘤学的妇女人数没有增加。在爱荷华州，我们已经发展了一个强大的32名导师，其中包括15名女教师与积极的研究计划，谁将解决妇女的特殊需要，在他们的辅导方法。我们建议教学会议，小组讨论和额外的个人辅导机会，以支持妇女寻求学术生涯。(END（见摘要）

DESCRIPTION (provided by applicant): We propose an institutional training grant to train physician/scientists who will contribute to improved diagnostic, treatment and prevention strategies for children with blood diseases and malignancies. Fellows will train in either translational or clinical research at the Children's Hospital of Iowa and the Roy J. and Lucille A. Carver College of Medicine. The University of Iowa is home to an academic medical center that provides the full range of health care including tertiary services for a large geographic area of predominantly rural families. A small, rapidly growing, minority population also lives and works in our catchment area and receives care in our institution. Our rural environment offers unique opportunities both for training pediatric subspecialists regarding hematologic and malignant diseases afflicting these children and for enrolling these children in clinical trials. We propose the following goals: 1. Expand opportunities for trainees to pursue academic careers with a focus on hematologic and malignant diseases of childhood. The Iowa Department of Pediatrics has an accredited ACGME fellowship program in hematology/oncology and has established a track record of recruiting highly qualified pediatricians who then pursue a career in academic medicine. In this application, we propose an institutional training program to focus on translational and clinical research in children with hematologic or malignant diseases. Our department currently has an NICHD training grant in neonatal biology and a NHLBI training grant in pediatric cardiology, thus providing important training support, including an established luncheon discussion series in which all pediatric subspecialty fellows participate, and a unique fellowship evaluation program specifically developed at Iowa. In this way, the entire Iowa Department of Pediatrics faculty will work together with experienced mentors in internal medicine, psychiatry, neurology, anatomy & cell biology, microbiology, physiology, anesthesia, radiology, radiation biology, and surgery to provide mentoring teams that provide a balanced training program in translational or clinical research that focuses on hematologic or oncologic diseases of childhood. Faculty in the College of Public Health participate in the K-30 program as well as in our formal evaluation program. 2. Provide trainees with the opportunity to obtain a Master's degree or non-degree certification in either translational or clinical medicine. The core curriculum for each fellow will be concentrated in either the University of Iowa K-30 program offering a master's in clinical research or in our unique University of Iowa graduate program in translational research. We have a well recognized expertise in basic medical science, as well as a growing expertise in clinical research among our proposed mentoring teams. Together, these strengths will form the foundation on which we will build a training program in translational or clinical research. Thus, in addition to certification or a master's degree in patient-oriented research, each fellow will have developed an individual research plan with sufficient preliminary data to submit a K-23 award at the completion of the fellowship. 3. Recruit and train women for successful careers that will benefit children with hematologic and oncologic disorders. The number of women entering medicine is steadily increasing. Nowhere is this more evident than in pediatric residency programs. Unfortunately, the number of women in academic pediatrics and in pediatric subspecialties such as pediatric hematology/oncology is not increasing. At Iowa, we have developed a strong group of 32 mentors, including 15 women faculty with active research programs, who will address the special needs of women in their mentoring approach. We propose didactic sessions, group discussions and additional individual mentoring opportunities to support women seeking academic careers. (END OF ABSTRACT)