Pediatric Endocrinology Research Training Program

描述(申请者提供)：该项目的目标是培训 高素质的年轻儿科医生在遗传学，发病机制， 包括糖尿病在内的儿科内分泌疾病的评估和处理 还有肥胖症。新陈代谢、免疫学和遗传学方面的培训 将强调该学科所涵盖的疾病。除 传统的儿科内分泌学、分子生物学、 分子遗传学和基因治疗将成为专题，因为这些新的 儿童内分泌疾病的诊断和治疗维度 必须由该领域未来的领导者掌握。在未来的收益中 对儿科内分泌疾病的理解将通过 基础与临床科学的融合和合作 来自多个不同学科的个人。国家科学家队伍 有能力在儿科内分泌学-糖尿病学方面取得下一步进展的是 严重受限。威尔-康奈尔大学的项目有着出色的记录 培训这样的领导者；然而，实验室有足够的保护时间 针对受训者的研究长期受到限制。儿科 本文所述的内分泌-糖尿病训练计划(儿科)基于 基础和临床科学家的协作指导 洛克菲勒韦尔-康奈尔医学院三机构综合体 斯隆-凯特林纪念大学和哥伦比亚大学附属学院 内科和外科医生。两名已完成实习的MD实习生 将接受一年的儿科内分泌学专科培训 加入该计划，每年接受两年的培训。符合条件的申请者 将通过内分泌协会和其他机构寻求少数民族的支持 具有少数族裔招聘目标的组织。对于每个实习生，有 将是必修的核心课程和参加研讨会和 研讨会，由积极资助的导师指导实验室培训 能够支持学员的调查经验的研究计划 在两年内。拥有广泛的专家咨询团队 相关学科将参加系列讲座和补充讲座 适合受训者研究兴趣的实验室培训。一个 杰出的执行委员会将确保凝聚力和重点使用 三机构综合体以及对该方案的持续评估。这个 这一研究培训计划的优势在于 讲师的专业知识和培训经验，是否有 儿科GCRC，一群杰出的咨询教师的承诺， 教职员工作为研究导师的成功展示，互动 在不同的教职员工和学员中，以及大量的研究 四个优秀研究机构的资源。全国性的需求 儿科临床见习的实验室培训 内分泌学家--糖尿病专家是敏锐的。这种内分泌的增长 肥胖、胰岛素抵抗综合征、糖尿病、高血压、 免疫介导的内分泌疾病以及肾上腺和卵巢遗传性疾病 憎恨挑战，这个应用程序就是为迎接挑战而设计的。

DESCRIPTION (provided by applicant): The goal of this program is to train highly qualified young pediatricians in the genetics, pathogenesis, evaluation, and management of pediatric endocrine disorders including diabetes and obesity. Training in metabolic, immunological and genetic aspects of the diseases encompassed by the discipline will be emphasized. In addition to the traditional core of training in Pediatric Endocrinology, molecular biology, molecular genetics and gene therapy will be featured, since these new dimensions for diagnosis and treatment of endocrine diseases of childhood will have to be mastered by future leaders of the field. Future gains in the understanding of pediatric endocrine diseases will come about through an integration of basic and clinical sciences and the collaboration of individuals from many and diverse disciplines. The national pool of scientists capable of making the next advances in pediatric endocrinology-diabetology is severely limited. The program at Weill-Cornell has an excellent record of training such leaders; however, sufficient protected time for laboratory research for trainees has been chronically constrained. The Pediatric Endocrine-Diabetes Training Program (Pediatrap) described herein is based on the collaborative mentorship of basic and clinical scientists at the tri-institutional complex of Well-Cornell College of Medicine, Rockefeller University, Memorial Sloan-Kettering, and affiliated Columbia College of Physicians & Surgeons. Two MD trainees who have completed residency and the first year of subspecialty training in Pediatric Endocrinology will be taken into the program for two years of training each year. Qualified applicants from ethnic minorities will be sought through the Endocrine Society and other organizations with minority recruitment objectives. For each trainee, there will be a required core course curriculum and attendance at seminars and symposia, with mentored laboratory training by preceptors with active funded research programs who can support the trainee's investigational experience over a 2-year period. A consulting faculty of experts in a wide range of related disciplines will participate in the lecture series and supplementary laboratory training appropriate to the trainee's research interests. A distinguished executive committee will ensure cohesive and focused use of the tri-institutional complex as well as ongoing evaluation of the program. The strengths of this research training program are the depth and breadth of expertise and training experience of the preceptors, the availability of a pediatric GCRC, the commitment of a distinguished group of consulting faculty, the demonstrated success of the faculty as research mentors, the interactions among the various faculty members and trainees, and the prodigious research resources of four outstanding research institutions. The national need for laboratory training of clinically informed pediatric endocrinologists-diabetologists is acute. The growth in such endocrine disorders as obesity, insulin resistance syndromes, diabetes, hypertension, immune-mediated endocrine diseases, and adrenal and ovarian genetic disorders resents a challenge, which this application is designed to meet.