Interactive Craniofacial Normative Database (Phase II)

描述(申请人提供)：在过去的二十年里，颅面人体测量学在临床遗传学和口腔颌面部整形外科中得到了越来越多的应用。定量测量使畸形特征的诊断既客观又可靠，这对遗传学家和外科医生都是一种恩惠。此外，手术计划也受益于这些指标，这些指标在评估术后成功方面很有用。这两方面的发展都得益于法卡斯的《头部和面部的人体测量学》的出版，该书于1981年首次出版，并在过去20年中进行了扩充和更新。这个颅面表面测量系统已经成为一个流行的标准参考，为北美提供了现存最广泛的标准化数据库。然而，由于目前没有商业上可用的计算机化数据库，用户目前有必要依赖繁琐的硬拷贝查询表，几乎不能访问变量的组合函数。我们的目标是通过创建一个基于计算机的交互式颅面测量数据库，使这些标准的使用更加人性化。我们的第一阶段项目成功地创建了该软件的CD-ROM版本，名为FaceValue，得到了用户的高度评价。在阶段2中，我们将实现此程序包的所有选项，并创建第二个基于Web的格式。最终产品的设计目的是：(1)使用菜单驱动的、具有里程碑意义的图形用户界面，便于随时访问以患者人口统计为条件的查找表；(2)允许计算患者的标准化测量，包括创建目前不可用但将由用户配置的功能；(3)提供来自现有数据库和头面部三维扫描仪的灵活输出选项，(4)生成人体测量协议的报告，条件是专业专业化，(5)实施数据安全和加密方法，以及(6)将导出的分数导出到数据库，以用于记录和统计分析。

DESCRIPTION (provided by applicant): Over the last two decades, craniofacial anthropometry has found increasing application in clinical genetics and oral maxillofacial and reconstructive plastic surgery. Quantitative measurements have rendered the diagnosis of dysmorphic features both objective and reliable, a boon to geneticists and surgeons alike. In addition, surgical planning has benefited from these metrics which are useful in the assessment of postoperative success. Both of these developments have been facilitated by the publication of Farkas' Anthropometry of the Head and Face, which first appeared in 1981 and which has been expanded and updated over the last 20 years. This craniofacial surface measurement system has become a popular standard reference, providing the most extensive normative database extant for North America. Nevertheless, because there is no commercially available computerized database at the present, it is currently necessary for the user to rely on cumbersome hard-copy look-up tables with little access to combined functions of variables. Our objective within this STTR is to make the use of these norms more user-friendly by creating a computer-based interactive craniofacial measurement database for them. Our Phase 1 project successfully created a CD-ROM version of this software, entitled FaceValue, and this was highly rated by users. In Phase 2 we will implement all options for this package, and create a second, Web-based format. The final product is designed to (1) facilitate ready access to look-up tables conditioned on patient demographics, using a menu-driven, landmark-based graphic user interface; (2) permit computation of standardized measures for patients, including the creation of functions not currently available but which will be configured by the user; (3) provide flexible output options from pre-existing databases and craniofacial 3D scanners, (4) generate reports for anthropometric protocols, conditioned on professional specialization, (5) implement data security and encryption methods, and (6) export derived scores to databases for documentation and statistical analysis.