Nanotechnology in Biosensors and Bioengineering

描述(由申请人提供)： UAB的五个基础科学和工程系提出了一个跨学科的纳米生物技术计划，涉及物理、化学、材料科学、生理学和生物医学工程，目标是缩短从发现新的纳米技术工具或材料到将其应用于医疗器械、组织工程和生物传感器的时间。学员将被直接招募到五个参与的研究生项目中，并将参加共同的跨学科核心课程、特殊技能研讨会，以及在工业和国家实验室为期一学期的实习。培训领域包括用于牙科、骨科和心血管植入物的纳米结构生物材料，用于组织工程的纳米结构支架的生物反应器，纳米材料的细胞生物学，以及光学纳米生物传感器。我们请求为为期五年的四个博士后培训和一个博士后培训提供支持。博士后培训为期三年，博士后培训为期两年。该计划的参与者将有机会获得最先进的纳米技术工具和设施，以设计用于疾病检测、管理和预防的材料和生物传感器。我们的招募和保留目标是通过与少数族裔服务机构的合作，实现20%的少数族裔参与这一培训赠款。研究生顾问委员会将由参与部门的教师和一名临床教师组成，就纳米技术研究项目的临床相关性向学生提供建议。该计划将有一个由代表纳米技术组成部分的成员组成的外部顾问委员会，并将进行一年两次的外部评估。UAB政府正在分配资源，通过津贴补充和行政支持来建立、维持和制度化这一跨学科培训计划，以开展全国招聘，以吸引最合格的受训人员进入这一新兴的纳米生物技术领域。相关性：该培训计划将培养出一支高技能的劳动力队伍，将纳米技术应用于生物医学植入物、用于疾病早期诊断的生物传感器和再生医学。纳米技术方法将提高生物医学植入物的寿命和功能，并改善人类健康。

DESCRIPTION (provided by applicant): Five basic science and engineering departments at UAB propose an interdisciplinary nanobiotechnology program at the interfaces of physics, chemistry, materials science, physiology, and biomedical engineering with a goal of reducing the time from discovery of a new nanotechnology tool or material to its application in medical devices, tissue engineering and biosensors. The trainees will be directly recruited in to the five participating graduate programs and will attend common interdisciplinary core courses, special-skills workshops, and a semester-long internship at the industrial and national lab sites. Areas for training include nanostructured biomaterials for dental, orthopedic, and cardiovascular implants, bioreactors for nanostructured scaffolds for tissue engineering, cell biology on nanoscale materials, and optical nanobiosensors. We request support for four predoctoral trainnes and one postdocdoctoral training for a five year period. The predoctoral training will be for a three year period while the postdoctoral training will be for a two year period. The participants in this program would have access to the state of the art nanotechnology tools and facilities to design materials and biosensors for disease detection, management, and prevention Our recruitment and retention goal is to achieve 20% minority participation in this training grant through partnerships with minority serving institutions. The graduate students advisory committee will consist of faculty from the participating departments and a clinical faculty member to advise student on the clinical relevance of nanotechnology research projects. This program will have an external advisory board with members representing nanotechnology constituents and will conduct a biannual external assessment. UAB administration is allocating resources to build, sustain and institutionalize this interdisciplinary training program through stipend supplements and administrative support to carry out a national recruitment to attract the best-qualified trainees to this emerging field of nanobiotechnology. Relevance: This training program would produce a highly skilled workforce that will apply nanotechnology to biomedical implants, biosensors for early diagnostics of diseases and regenrative medicine. Nanotechnology approaches will impove the longevity and function of biomedical implants and improve human health.