Duke Training Grant in Digestive Diseases and Nutrition

描述（由申请人提供）： 本培训计划的目标是培养一批选定的医学博士。和博士研究人员在学术胃肠病学的基础和临床研究的职业生涯。完成本课程后，学员将有资格担任医学院教师职位，进行独立的调查计划，并教学和参与临床活动。该计划的研究方向强调与消化疾病和营养的细胞，器官和综合机制研究相关的生理学，细胞生物学和分子生物学技术。研究结果为胃肠道疾病的临床治疗提供了学术发展的基础。 在过去的15年里，我们已经培训了超过25名博士前和博士后候选人。这些人中有70%以上的人继续担任学术职务，其中许多人得到了校外资助。自上次申请以来，我们已经修改了培训教师，删除了几个不是GI部门教师的培训师，并从GI部门增加了新的培训师和助理培训师。培训教师都是NIH，VA和/或行业资助的临床和基础研究的研究人员。我们要求每年为四名学员提供支持，这是由于培训机会的扩大、培训计划的总体成功以及合格申请人的数量。我们将继续招收合格的博士。少数民族候选人的代表性不足。 基本培训计划包括在一个或多个教师调查员的直接监督下进行密集的实验室研究。这是通过研究生院，研讨会和期刊俱乐部的正式课程工作的补充。此外，胃肠病学的临床培训是通过参加由杜克大学医学中心和达勒姆退伍军人事务医疗中心胃肠病学分部成员提供的大型住院、门诊和外展咨询服务提供的。临床研究培训包括正式的课程工作和实际动手培训。鼓励该计划的个人获得健康科学硕士学位。这些培养目标的实现将有助于培养能够在临床和基础领域进行高水平研究的医生-科学家

DESCRIPTION (provided by applicant): The objective of this training program is to develop a selected group of M.D. and Ph.D. investigators for careers in basic and clinical research in academic gastroenterology. Upon completion of this program, trainees will be qualified to assume medical school faculty positions, conduct independent programs of investigation, and teach and participate in clinical activities. The research orientation of the program emphasizes techniques in physiology, cell biology and molecular biology relevant to the study of cell, organ and integrated mechanisms of digestive disease and nutrition. In outcomes provide a basis of academic development in clinical treatments of gastrointestinal disease. With previous NIH training grant support over the past 15 years we have trained over 25 pre- and post-doctoral candidates. Over seventy percent of these individuals have gone on to academic positions and many of these have extramural grant support. Since the last application, we have revised the training faculty, removing several trainers that were not Gl Divisional faculty and adding new trainers and associate trainers from the Gl Division. The training faculty are all NIH, VA and/or industry-funded investigators in clinical and basic research. We request support for four trainees per year, justified by the expanded training opportunities, the overall success of the training program and the number of qualified applicants. We shall continue to recruit qualified Ph.D. and under represented minority candidates. The basic training program consists of an intensive laboratory-oriented research experience under the direct supervision of one or more faculty investigators. This is supplemented with formal course work through the graduate school, seminars, and journal clubs. In addition, clinical training in gastroenterology is provided by participation in large inpatient, outpatient and outreach consult services staffed by members of the Division of Gastroenterology at Duke University Medical Center and Durham Veterans Affairs Medical Center. Training in clinical research involves formal course work and practical hands-on training. Individuals in this program are encouraged to obtain a Master's Degree in Health Sciences. Fulfillment of these training goals will serve to develop physician-scientists who can conduct high caliber research in both clinical and basic