Chronic Prostatitis Collaborative Research Network

这项申请的目标是在加州大学洛杉矶分校建立一个临床试验中心，哈伯勒加州大学洛杉矶分校医学中心，以及 马丁·路德·金-德鲁医疗中心将参与合作的多地点临床试验 由新成立的NIDDK赞助的慢性前列腺炎合作研究网络主办 (CPCRN)。作为CPCRN网站，加州大学洛杉矶分校将 (1)参与治疗相关症状的随机对照临床试验设计 患有慢性前列腺炎，也称为慢性盆腔疼痛综合征(CPPS) (2)开发和进行辅助研究，以加深对CPPS的了解 (3)确定不同分组的患者对治疗的反应是否不同，包括 新诊断和慢性长期CPPS患者 (4)招募足够数量的CCPS患者，包括足够数量的新患者 确诊病例，进入这些临床试验 (5)与CPCRN的其他调查人员，包括数据协调中心合作，分析和 解读审判结果 (六)参加新成立的泌尿外科慢性盆腔疼痛综合征协作组 促进间质性膀胱炎和慢性前列腺炎的临床试验的有效进行 这项研究将为泌尿系慢性盆腔疼痛综合征制定一个临床相关的定义，其基础是 这些临床研究和其他相关临床研究的临床结果。加州大学洛杉矶分校的网站已经展示了 招募少数族裔受试者参加CPPS的研究，包括临床试验的经验 以及其他泌尿系统疾病。加州大学洛杉矶分校的网站将建立在它作为第一个包租网站的经验基础上 CPCRN要实现第二个确定的目标。

The goal of this application is to establish a clinical trial center at UCLA, HarborlUCLA Medical Center, and Martin Luther King-Drew Medical Center that will participate in collaborative, multi-site clinical trials sponsored by a newly established NIDDK-sponsored Chronic Prostatitis Collaborative Research Network (CPCRN). As a CPCRN site, UCLA will (1) participate in the design of randomized controlled clinical trials to treat the symptoms associated with chronic prostatitis, also known as chronic pelvic pain syndrome (CPPS) (2) develop and conduct ancillary studies, which will provide further understanding of CPPS (3) determine if there is a different response to therapy between sub-groups of patients, including newly diagnosed and chronic, long-term patients with CPPS (4) recruit sufficient numbers of patients with CCPS, including an adequate number of newly diagnosed cases, into these clinical trials (5) jointly work with other CPCRN investigators, including a Data Coordinating Center, to analyze and interpret the results of the trials (6) participate in a newly established Urological Chronic Pelvic Pain Syndromes Collaborative Group to facilitate the efficient conduct of clinical trials in both interstitial cystitis and chronic prostatitis The study will develop a clinically relevant definition of the urologic chronic pelvic pain syndromes, based on the clinical findings from these and other related clinical studies. The UCLA site has demonstrated experience in recruiting minority subjects to participate in research studies, including clinical trials, for CPPS and other urologic conditions. The UCLA site will build upon its experience as a charter site in the first CPCRN to achieve the goals set out by the second.