Chronic Prostatitis Collaborative Research Network

慢性前列腺炎合作研究网络

• 批准号: 7046826
• 负责人: MARK S. LITWIN
• 金额: $ 25.91万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-05 至 2008-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7046826
• 关键词: chronic disease /disorder; clinical research; clinical trials; cooperative study; diagnosis design /evaluation; disease /disorder classification; disease /therapy duration; experimental designs; human subject; human therapy evaluation; male; medical outreach /case finding; nonsteroidal antiinflammatory agent; pain; patient oriented research; pelvis; prostatitis; reproductive system disorder chemotherapy; reproductive system disorder diagnosis

DESCRIPTION (provided by applicant): The goal of this application is to establish a clinical trial center at UCLA, Harbor UCLA Medical Center, and Martin Luther King-Drew Medical Center that will participate in collaborative, multi-site clinical trials sponsored by a newly established NIDDK-sponsored Chronic Prostatitis Collaborative Research Network (CPCRN). As a CPCRN site, UCLA will (1) participate in the design of randomized controlled clinical trials to treat the symptoms associated with chronic prostatitis, also known as chronic pelvic pain syndrome (CPPS) (2) develop and conduct ancillary studies, which will provide further understanding of CPPS (3) determine if there is a different response to therapy between sub-groups of patients, including newly diagnosed and chronic, long-term patients with CPPS (4) recruit sufficient numbers of patients with CCPS, including an adequate number of newly diagnosed cases, into these clinical trials (5) jointly work with other CPCRN investigators, including a Data Coordinating Center, to analyze and interpret the results of the trials (6) participate in a newly established Urological Chronic Pelvic Pain Syndromes Collaborative Group to facilitate the efficient conduct of clinical trials in both interstitial cystitis and chronic prostatitis The study will develop a clinically relevant definition of the urologic chronic pelvic pain syndromes, based on the clinical findings from these and other related clinical studies. The UCLA site has demonstrated experience in recruiting minority subjects to participate in research studies, including clinical trials, for CPPS and other urologic conditions. The UCLA site will build upon its experience as a charter site in the first CPCRN to achieve the goals set out by the second.

描述（由申请人提供）： 该申请的目标是在 UCLA、Harbor UCLA 医疗中心和 Martin Luther King-Drew 医疗中心建立一个临床试验中心，该中心将参与由新成立的 NIDDK 资助的慢性前列腺炎协作研究网络 (CPCRN) 赞助的协作性多地点临床试验。作为 CPCRN 站点，加州大学洛杉矶分校将 (1) 参与设计随机对照临床试验，以治疗与慢性前列腺炎（也称为慢性盆腔疼痛综合征 (CPPS)）相关的症状 (2) 开发和开展辅助研究，这将提供对 CPPS 的进一步了解 (3) 确定患者亚组之间是否存在不同的治疗反应，包括新诊断的 CPPS 患者和慢性、长期 CPPS 患者 (4) 招募足够数量的 CCPS 患者，包括足够数量的新诊断病例，参与这些临床试验 (5) 与包括数据协调中心在内的其他 CPCRN 研究人员共同分析和解释试验结果 (6) 参加新成立的泌尿科慢性盆腔疼痛综合征协作组，以促进间质性和间质性临床试验的高效进行 膀胱炎和慢性前列腺炎 该研究将根据这些和其他相关临床研究的临床结果，制定泌尿科慢性盆腔疼痛综合征的临床相关定义。加州大学洛杉矶分校在招募少数受试者参与 CPPS 和其他泌尿系统疾病的研究（包括临床试验）方面拥有丰富的经验。加州大学洛杉矶分校站点将借鉴其作为第一个 CPCRN 特许站点的经验，实现第二个 CPCRN 设定的目标。