Chronic Prostatitis Collaborative Research Network

描述(由申请人提供)： 该应用程序的目标是在加州大学洛杉矶分校、加州大学洛杉矶分校港湾医学中心和马丁·路德·金-德鲁医学中心建立一个临床试验中心，该中心将参与由新成立的NIDDK赞助的慢性前列腺炎合作研究网络(CPCRN)赞助的多地点协作临床试验。作为CPCRN网站，加州大学洛杉矶分校将(1)参与治疗与慢性前列腺炎(也称为慢性盆腔疼痛综合征(CPPS))相关症状的随机对照临床试验的设计(2)开发和进行辅助研究，这将提供对CPPS的进一步了解(3)确定包括新诊断的和慢性的、长期的CPPS患者在内的患者分组之间是否对治疗有不同的反应(4)招募足够数量的CCPS患者，包括足够数量的新诊断病例进入这些临床试验(5)与其他CPCRN调查人员合作，包括数据协调中心，为了分析和解释试验的结果(6)参加一个新成立的泌尿系统慢性盆腔疼痛综合征协作组，以促进间质性膀胱炎和慢性前列腺炎的临床试验的有效进行，这项研究将根据这些和其他相关临床研究的临床结果，制定一个与临床相关的泌尿系统慢性盆腔疼痛综合征的定义。加州大学洛杉矶分校的网站在招募少数族裔受试者参与包括临床试验在内的CPPS和其他泌尿系统疾病的研究方面表现出了经验。加州大学洛杉矶分校的场地将建立在其作为第一个CPCRN包租场地的经验基础上，以实现第二个CPCRN设定的目标。

DESCRIPTION (provided by applicant): The goal of this application is to establish a clinical trial center at UCLA, Harbor UCLA Medical Center, and Martin Luther King-Drew Medical Center that will participate in collaborative, multi-site clinical trials sponsored by a newly established NIDDK-sponsored Chronic Prostatitis Collaborative Research Network (CPCRN). As a CPCRN site, UCLA will (1) participate in the design of randomized controlled clinical trials to treat the symptoms associated with chronic prostatitis, also known as chronic pelvic pain syndrome (CPPS) (2) develop and conduct ancillary studies, which will provide further understanding of CPPS (3) determine if there is a different response to therapy between sub-groups of patients, including newly diagnosed and chronic, long-term patients with CPPS (4) recruit sufficient numbers of patients with CCPS, including an adequate number of newly diagnosed cases, into these clinical trials (5) jointly work with other CPCRN investigators, including a Data Coordinating Center, to analyze and interpret the results of the trials (6) participate in a newly established Urological Chronic Pelvic Pain Syndromes Collaborative Group to facilitate the efficient conduct of clinical trials in both interstitial cystitis and chronic prostatitis The study will develop a clinically relevant definition of the urologic chronic pelvic pain syndromes, based on the clinical findings from these and other related clinical studies. The UCLA site has demonstrated experience in recruiting minority subjects to participate in research studies, including clinical trials, for CPPS and other urologic conditions. The UCLA site will build upon its experience as a charter site in the first CPCRN to achieve the goals set out by the second.