Cancer Center Support Grant

描述（由申请人提供）：印第安纳大学癌症中心是一个矩阵癌症中心，组织和促进癌症研究、教育、患者护理和癌症控制和预防，以实现其降低印第安纳州及其他地区癌症的发病率、发病率和死亡率的使命。该申请为中心的5个研究项目、11个共享设施、协议特定研究以及协议审查和监测系统寻求资金。此外，还要求为行政、计画规划与评估、发展基金和高级领导人提供资金。研究项目的组织和发展是高度互动的，允许基础和临床研究人员之间的成功合作。主要研究方向为：1)行为肿瘤学与癌症预防；2)乳腺癌；3)实验治疗学；3)造血与免疫学；5)细胞生长调控。支持这些项目成员的是11个共享资源：生物显微镜、生物统计学和数据管理、临床研究办公室、基因分型和基因表达、流式细胞术、病理学、体内成像、蛋白质组学和蛋白质表达、转基因和敲除小鼠核心、移植和异种移植小鼠核心以及载体生产。

DESCRIPTION (provided by applicant): The Indiana University Cancer Center is a matrix Cancer Center that organizes and facilitates cancer research, education, patient care, and cancer control and prevention to accomplish its mission of reducing the incidence, morbidity, and mortality of cancer in Indiana and beyond. This application seeks funds for the Center's five research programs, eleven shared facilities, Protocol-Specific Research, and a Protocol Review and Monitoring System. In addition, funds are requested for Administration, Program Planning and Evaluation, Developmental Funds, and Senior Leaders. The research programs have been organized and developed to be highly interactive, allowing for successful collaboration among basic and clinical researchers. The research programs are: 1) Behavioral Oncology and Cancer Prevention, 2) Breast Cancer, 3) Experimental Therapeutics, 3) Hematopoiesis and Immunology, and 5) Regulation of Cell Growth. Supporting the members of these programs are eleven shared resources: Biological Microscopy, Biostatistics and Data Management, Clinical Research Office, Genotyping and Gene Expression, Flow Cytometry, Pathology, In Vivo Imaging, Proteomics and Protein Expression, Transgenic and Knock-out Mouse Core, Transplant and Xenograft Mouse Core, and Vector Production.