Halting the spread multidrug resistant uropathogenic E. coli
Halting the spread multidrug resistant uropathogenic E. coli
批准号:
nhmrc : GNT1106930
负责人:
Prof Mark Schembri
金额:
$68.8万
依托单位国家:
澳大利亚
项目类别:
Research Fellowships
财政年份:
2016
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2016-01-01 至 --
中文摘要
尿路致病性大肠埃希菌(UPEC)是引起尿路感染(UTI)的主要原因之一,并与多种抗生素的耐药性密切相关。该项目将研究耐多药UPEC的毒力,并利用这一知识开发治疗和预防尿路感染的新方法。结果将适用于人类最常见的传染病之一,并对我们理解由革兰氏阴性病原体引起的其他感染产生广泛影响。
英文摘要
Uropathogenic Escherichia coli (UPEC) is a major cause of urinary tract infection (UTI) and increasingly associated with resistance to multiple antibiotics. This project will study the virulence of multidrug resistant UPEC and use this knowledge to develop new approaches to treat and prevent UTI. The outcomes will be applicable to one of the most common infectious diseases of humans and have broad-reaching impact on our understanding of other infections caused by Gram-negative pathogens.
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