INSTRUMENTATION FOR ANGULAR LIGHT SCATTERING SPECTROSCOPY

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。在这个项目中，理论和实验之间有着密切的相互作用。我们对组织的光谱和角光散射特性的了解的精细化导致了我们的ALSS仪器的不断重新设计和优化。这些变化是必要的，因为ALSS从一项仅致力于核大小表征的技术发展到一项也试图在亚微米范围内表征组织和细胞形态的技术。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. There is a close interplay in this project between theory and experiment. Refinement of our understanding of spectral and angular light scattering properties from tissue leads to continual redesign and optimization of our ALSS instrumentation. These changes are necessary as ALSS develops from a technique solely devoted to nuclear size characterization to one which also attempts to characterize tissue and cellular morphology at the sub-micron range.