Harnessing the consequences of impaired mitochondrial function to treat and image motor neuron disease

运动神经元病(MND)是一组致命的成人发病疾病，影响从大脑向肌肉传递信号的神经元。由于人口老龄化，MND的发病率正在迅速增加，MND的诊断伴随着瘫痪和2-5年生存的预后。诊断过程漫长，即使在MND确诊后，也没有有效的治疗方法。该研究项目旨在为MND开发新的治疗和诊断方案。

Motor neuron disease (MND) is a group of fatal adult-onset diseases affecting the neurons that relay signals from the brain to muscles. The incidence of MND is rapidly increasing due to the ageing population and a diagnosis of MND comes with a prognosis of paralysis and 2-5 years survival. The diagnosis process is lengthy, and even after MND is confirmed, there are no effective therapeutics. This research project aims to develop new therapeutic and diagnostic options for MND.