LONGITUDINAL STUDY OF OCULAR COMPLICATIONS OF AIDS (LSOCA)

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。这项研究的目的是了解艾滋病毒感染及其治疗如何影响人们的眼睛和视力。本研究的目的是：1）监测艾滋病眼部并发症发病率的长期趋势; 2）确定HAART诱导的免疫状态变化对艾滋病眼部并发症发病率和病程的影响; 3）确定使其处于眼部并发症高危状态的患者的特征;评估CMV视网膜炎和其他眼部并发症的治疗对视功能、生活质量和生存率的影响。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this research study is to learn how HIV infections and its treatments affect people's eyes and their sight. The objectives of this study are: 1) to monitor secular trends in the incidence of ocular complications of AIDS; 2) to determine the effect of HAART-induced changes in immune status of the incidence and course of ocular complications of AIDS; 3) to determine the characteristics of patients that place them at high risk for ocular complications; and 4) to evaluate the effects of treatments for CMV retinitis and other ocular complications on visual function, quality of life, and survi