CCTG 560A: VIRAL POPULATION KINETICS

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。评估开始或停止抗逆转录病毒治疗后的艾滋病毒产生率和清除率。在开始或停止抗逆转录病毒治疗后，评估不同病毒种群的动态（根据耐药模式或宿主细胞）。评估血浆中检测到HIV RNA和未检测到HIV RNA的受试者淋巴组织中的病毒数量，并评估血浆中检测不到HIV RNA水平时淋巴细胞中的病毒数量。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Evaluate the rates of HIV production and clearance after initiating or discontinuing antiretroviral treatment. Evaluate the dynamics of different virus populations (according to resistance pattern or host cell) after initiating or discontinuing antiretroviral treatment. Evaluate viral populations in lymph tissue in subjects with and without detectable HIV RNA in the plasma, and evaluate viral populations in lymphocytes when HIV RNA levels are undetectable in the plasma.