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MECHANISMS UNDERLYING ENHANCED ALVEOLAR MACROPHAGE ACCESSORY FUNCTION IN HIV

MECHANISMS UNDERLYING ENHANCED ALVEOLAR MACROPHAGE ACCESSORY FUNCTION IN HIV
HIV 肺泡巨噬细胞辅助功能增强的机制
批准号：
7379043
负责人：
Homer L Twigg
金额：
$0.44万
依托单位：
INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS
依托单位国家：
美国
项目类别：
财政年份：
2005
资助国家：
美国
项目状态：
已结题
起止时间：
2005-12-01 至 2006-11-30
来源：
https://reporter.nih.gov/project-details/7379043
关键词：
MECHANISMSUNDERLYINGENHANCEDALVEOLARMACROPHAGE

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中文摘要
翻译
这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。目前的研究旨在研究这种增强的潜在机制，寻找各种因素，并将细胞间的相互作用作为潜在的介体。静息和激活的AM释放某些促进淋巴增殖的细胞因子的能力将被测量。
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The current study is designed to investigate mechanisms underlying this enhancement looking at factors and direct cell to cell interactions as potential mediators. The ability of resting and activated AM to release certain lymphoproliferative enhancing cytokines will be measured.
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