INFLUENZA IMMUNITY: INFLUENZA VACCINE IN CHILDREN 5-9 YEARS OF AGE

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。一项关于5-9岁儿童接种两种特许流感疫苗(肌肉注射灭活疫苗或鼻内注射减毒活疫苗)的免疫反应的IV期、单中心、随机研究。接下来是每周一次的鼻拭子，在当地流感季节分析大流行性呼吸道病毒(PCR)的证据，并在接种后分析流感症状的日记卡片

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. A Phase IV, single-center, randomized study of the immune responses of 5-9 yr-old children given one of two licensed influenza vaccines (either inactivated vaccine given intramuscularly (IM) or live, attenuated vaccine given intranasally). A subset will be followed with weekly nasal swabs to be analyzed for Pandemic Respiratory Virus (PCR) evidence of influenza virus during the local influenza season and diary cards for flu symptoms following immunizat