THE EFFECTS OF STANDARD FEEDING VS ENTERAL INFUSION ON DE NOVO LIPOGENESIS

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。这项研究调查了膳食脂肪在人类中的命运。用喂管喂食的受试者在用嘴进食食物时进行了重新研究。我们的目标是确定(1)食物摄入后有多少膳食脂肪被燃烧，有多少进入肝脏；(2)人体肝脏中有多少膳食碳水化合物被转化为脂肪；以及(3)两种喂养方式(管饲和口服)是否会影响这些过程。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This study investigated the fate of dietary fat in humans. Subjecs who had been fed using a feeding tube were restudied when food was consumed by mouth. Our goals were to determine (1) how much dietary fat is burned after food consumption and how much enters the liver; (2) how much dietary carbohydrate is made into fat in the human liver, and (3) whether the two modes of feeding (tube feeding vs. oral consumption) affect these processes.