ROLE OF MONTELUKAST ON PERENNIAL ALLERGIC RHINITIS & ASSOCIATED SLEEP DISTURBANC

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。本研究的假设是，白三烯受体拮抗剂（LRA）孟鲁司特（Montelukast）可以减少鼻塞，从而增加鼻腔通畅，减少夜间睡眠碎片。减少睡眠碎片会减少白天的嗜睡和疲劳。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The hypothesis for this study is that a leukotriene receptor antagonist (LRA), Montelukast, will decrease nasal congestion leading to increased patency of the nose and a decrease in nighttime sleep fragmentation. This decrease in sleep fragmentation will reduce daytime somnolence and fatigue.