YOUTH TYPE 1 DIABETES NONADHERENCE PREVENTION PROGRAM

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。本方案旨在进行一项随机对照试验，以评估是否可以通过向青春期前患者提供持续2个月以上的糖尿病依从性干预来改善儿童糖尿病的健康结局。该干预措施将针对所有青春期前儿童，无论其先前的依从性水平如何。治疗后1、3和6个月，将在基线和再次评估依从性的客观测量，以及自我和父母对行为功能的报告。作为这项研究的一部分，年龄在10-11岁的被诊断为1型糖尿病至少6个月的青春期前儿童及其父母将被随机分配接受常规医疗访问期间提供的标准糖尿病教育（SDE）或SDE加上心理社会增强依从性促进计划（SDE+AP）。该项目将以小组形式实施，为期2个月，由一名训练有素的行为健康咨询师和一名心理学家领导。在研究随访期间，依从性促进有望减少不依从性并稳定代谢功能。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This protocol seeks to conduct a randomized controlled trial to evaluate whether the health outcomes of childhood diabetes can be improved by providing a diabetes adherence intervention over 2 months duration to preadolescents. The intervention will target all preadolescents, regardless of prior adherence level. Objective mwasures of adherence, and self- and parent-reports of behavioral functioning, will be assessed at baseline and again 1, 3, and 6 months post-treatment. As part of this study, preadolescent children ages 10-11 years old who have been diagnosed with Type 1 diabetes for at least 6 months, and their parents, will be randomized to recieve either standard diaberes education (SDE) provided during routine medial visits or SDE plus a psychosocially enhanced adherence promotion program (SDE+AP). The program will be implemented in a group format over the course of a 2 month period, and will be led by a trained behavioal health counselor and a psychologist. Adherence promotion is expected to result in decreased non-adherence and stabilized metabolic functioning during the study's follow-up period.