ACTG A5223: SEX DIFFERENCES IN LOPINAVIR / RITONAVIR PHARMACOKINETICS

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。本研究旨在评价基于患者性别的洛匹那韦/利托那韦血液水平是否存在差异。此外，这项PK研究将确定人种、种族、年龄、体重、体重指数和使用替诺福韦对洛匹那韦和利托那韦水平的影响。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This study is to evaluate if there are differences in the Lopinavir/Ritonavir blood levels based on the sex of the patient. In addition, this PK study will determine the effect of race, ethnicity, age, weight, body mass index and the use of Tenofovir on the levels of Lopinavir and Ritonavir.