University of Cincinnati CTSA Planning Grant

描述（申请人提供）：辛辛那提大学（UC）临床和转化科学奖（CTSA）规划补助金申请的总体目标是规划机构CTSA申请，我们将通过改变UC学术健康中心（AHC）当前的临床和转化研究环境，为临床和转化研究开发一个学术之家，它由3个组织上独立但合作的医疗中心组成：辛辛那提大学医疗中心、辛辛那提儿童医院医疗中心和辛辛那提退伍军人事务医疗中心。正如其对一般临床研究中心，K30，试点项目计划，转化研究计划，计算医学中心，生物信息学计划，生物统计学和研究设计核心的大力支持所证明的那样，UC AHC管理部门大力支持临床和转化以及计划中的机构CTSA。 机构CTSA将在医学院院长办公室的新临床和转化科学与培训中心内创建。该中心的目标与机构CTSA的目标完全一致，由Joel Tsevat，MD，MPH和James Heubi，MD，co-Pis共同指导。CTSA规划过程将涉及每个潜在机构CTSA重点领域的需求分析：试点和协作转化和临床研究;生物医学信息学;新型临床和转化方法;设计，生物统计学和伦理学;参与者和临床互动资源;社区参与;教育，培训和职业发展;以及监管知识和支持。由整个UC学术健康中心及其社区合作伙伴的利益相关者组成的工作组将在全年定期与Tsevat博士，Heubi博士和咨询委员会会面，以严格评估每个重点领域，并提出打破现有障碍的方法来开展合作跨学科临床和转化研究。我们将评估实际的规划过程，并计划评估机构CTSA的发展，实施和有效性。我们预计，机构CTSA过程将改变临床和转化科学和培训在当地和全国范围内进行的方式。

DESCRIPTION (provided by applicant): The overarching goal of the University of Cincinnati (UC) Clinical and Translational Science Award (CTSA) Planning Grant application is to plan an Institutional CTSA application, in which we will develop an academic home for clinical and translational research by transforming the current clinical and translational research environment at the UC academic health center (AHC), which is comprised of 3 organizationally separate but partnering medical centers: University of Cincinnati Medical Center, Cincinnati Children's Hospital Medical Center, and the Cincinnati Veterans Affairs Medical Center. As evidenced by its strong support of its General Clinical Research Center, K30, pilot project programs, Translational Research Initiative, Computational Medicine Center, bioinformatics programs, biostatistics and study design cores, the UC AHC administration is strongly supportive of clinical and translational and the planned Institutional CTSA. The Institutional CTSA will be created within the new Center for Clinical and Translational Science and Training in the Office of the Dean of the College of Medicine. The Center, whose goals are perfectly aligned with the goals of the Institutional CTSA, is co-directed by Joel Tsevat, MD, MPH and James Heubi, MD, co-Pis on this CTSA Planning Grant. The CTSA planning process will involve a needs analysis of each of the potential Institutional CTSA focus areas: pilot and collaborative translational and clinical studies; biomedical informatics; novel clinical and translational methodologies; design, biostatistics and ethics; participant and clinical interactions resources; community engagement; education, training and career development; and regulatory knowledge and support. Working groups comprised of stakeholders from the entire UC academic health center and its community partners will meet regularly throughout the year with Dr. Tsevat, Dr. Heubi, and an advisory board to critically assess each focus area and propose ways to break down existing barriers to carrying out collaborative interdisciplinary clinical and translational research. We will evaluate the actual planning process and plan the evaluation of the Institutional CTSA's development, implementation, and effectiveness. We anticipate that the Institutional CTSA process will transform the way that clinical and translational science and training is carried out both locally and nationally.