Research Training In Transfusion Medicine

描述(由申请人提供)：这是一份修订后的申请，申请31-35年的机构补助金，以支持输血医学科学的博士后研究培训。自从2002年的上一次竞争性更新以来，威斯康星州血液中心(BCW)资助的研究增加了一倍多，可供导师研究员使用的师资从11人增加到17人。2006年12月完成的血液研究所的扩建使可用的研究空间大约翻了一番。一项协议正在与威斯康星州医学院(MCW)谈判，根据该协议，血液中心的医生将负责在主要的MCW教学机构弗罗德特纪念路德医院(Froedtert Memory Lutheran Hospital)的“经典”血液学。这些发展将增加基础研究培训机会，为临床/转化性研究开辟新的途径，并为培训助学金教师提供前所未有的机会，接触对研究培训感兴趣的住院医生和研究员。 学员可获得的研究机会涵盖与输血科学相关的广泛临床和基础研究课题，包括免疫学、血管生物学/止血、输血医学、干细胞生物学和临床试验。研究培训体验基本上将是全职的。受训人员将被要求对他们从事研究的学科有一个基本的了解，熟悉各种研究方法，通过参加妇幼保健院研究生课程的精选课程来加强他们对基础科学的掌握，并发展进行独立研究的能力。花在团契培训上的时间被认为是专业发展的几个阶段之一。因此，还将为选定的学员提供额外的培训途径，包括1)申请临床研究人员发展奖(KO8)以继续指导，申请独立资助，3)面向输血医学职业生涯的学员，作为S血液中心的初级医务人员进行进一步培训的机会。最终，学员将选择输血学或与之密切相关的学科，如免疫血液学、移植免疫学、血管生物学、止血/血栓形成或干细胞生物学。

Description (provided by applicant): This is a revised application requesting funding for Years 31-35 of an Institutional Grant to support postdoctoral research training in transfusion medicine sciences. Since the last competitive renewal in 2002, funded research at the BloodCenter of Wisconsin (BCW) has more than doubled, and faculty available to mentor fellows has increased from 11 to 17. Available research space has been roughly doubled by an addition to the Blood Research Institute completed in December, 2006. An agreement is being negotiated with the Medical College of Wisconsin (MCW) under which Blood Center physicians will take responsibility for "classical" hematology at the Froedtert Memorial Lutheran Hospital, the major MCW teaching facility. These developments will enhance basic research training opportunities, open new avenues for clinical/translational research and provide training grant faculty with unprecedented access to residents and fellows who have an interest in research training. Research Opportunities available to trainees cover a broad range of clinical and basic research subjects relevant to transfusion science, including Immunology, Vascular Biology/Hemostasis, Transfusion Medicine, Stem Cell Biology and Clinical Trials. The research training experience will be essentially full time. Trainees will be expected to gain a basic understanding of the disciplines in which they undertake their investigations, become familiar with a variety of research methodologies, strengthen their grasp of basic science by taking selected courses in the graduate studies program of MCW and develop the ability to conduct independent research. Time spent in fellowship training is regarded as one of several stages of professional development. Accordingly additional tracks will be offered to selected trainees, including the opportunity 1) to apply for a Clinical Investigator Development Award (KO8) for continued mentoring, to apply for independent grant support, and 3) for those oriented toward a career in transfusion medicine, an opportunity for further training as a junior member of The BloodCenter"s medical staff. Ultimately, trainees are expected to pursue academic careers in transfusion science or a closely related discipline such as immunohematology, transplantation immunology, vascular biology, hemostasis/thrombosis or stem cell biology.