Research training in HIV-related transfusion medicine and hematology in South Africa
南非艾滋病毒相关输血医学和血液学研究培训
基本信息
- 批准号:10248622
- 负责人:
- 金额:$ 7.3万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2017
- 资助国家:美国
- 起止时间:2017-08-15 至 2022-07-31
- 项目状态:已结题
- 来源:
- 关键词:AIDS-Related LymphomaAddressAfricanAnemiaBiologicalBiological AssayBiometryBloodCaliforniaClinical ResearchCollaborationsCountryData AnalysesDatabasesDevelopmentDisciplineDoctor of PhilosophyEpidemicFacultyFundingGrantHIVHIV InfectionsHIV therapyHealth SciencesHealth Services ResearchHematologistHematologyIncidenceInstitutesInternationalInternshipsManuscriptsMeasuresMedicalMentorsNational Heart, Lung, and Blood InstituteNeeds AssessmentPatientsPreparationPrevalenceProtocols documentationRecording of previous eventsResearchResearch DesignResearch InfrastructureResearch InstituteResearch MethodologyResearch Project GrantsResearch TrainingRisk FactorsSan FranciscoSchoolsScientistSeriesServicesSouth AfricaSouth AfricanSpecimenTrainingTraining ProgramsTransfusionUniversitiesVascular blood supplyVisionWorkcareerdesignhuman capitalhuman subjectnovelprogramsresearch and developmentservice organizationskillssystems researchtransfusion medicinetrend
项目摘要
PROJECT SUMMARY/ABSTRACT
The proposed University of California San Francisco (UCSF)/Blood Systems Research Institute (BSRI),
University of Cape Town (UCT) and South Africa National Blood Service (SANBS) research training program in
HIV-related transfusion medicine and hematology research will train blood bankers and hematologists to
perform high-quality HIV research to address relevant research questions in South Africa. South Africa needs
research on its HIV epidemic's impact on the national blood supply and HIV-related hematology complications.
Since 2007, we have already accomplished a series of in-country short courses and identified a pool of 30-50
potential junior scientists for in-country HIV research in transfusion medicine and hematology among SANBS
staff and UCT junior faculty and medical postgraduates but their potential remains unfulfilled. This proposal
builds upon a 15-year history of HIV research collaboration between SANBS and UCSF/BSRI that yielded
research evidence to support a safe and adequate blood supply in South Africa. Under the NHLBI-funded
REDS-III International HIV research network, this collaboration will provide a funded research infrastructure for
trainees through 2019. Our needs assessment indicates that specific deficiencies in biostatistics, manuscript
preparation and research career mentoring need to be overcome to achieve our vision of a sustainable,
independent HIV-related transfusion medicine and hematology research enterprise in South Africa. We
propose Specific Aims of: 1) a research and development institute at SANBS; 2) an academic UCT
Hematology Division; and 3) broader human capital development to raise South Africa as a regional center of
excellence in this research. A three-tiered educational approach will be tailored to trainees at various levels of
their research careers: in-country short courses on clinical research methodology and protocol design will
reach a large number of trainees; for a smaller number lacking skills in study design, biostatistics and data
analysis we propose medium-term internships in Cape Town and San Francisco including course work and
research internships; finally, for a select few, Master's and PhD training in specific research disciplines will be
tailored to their needs at the UCT School of Health Sciences. Throughout, trainees will be mentored as they
accomplish their own research projects and compete for mini-grants funded by the program. The REDS-III HIV
research network will provide research opportunities in terms of access to human subjects, databases and
biological specimens. Research projects will address high-priority questions in HIV-related transfusion
medicine and hematology in South Africa, including: HIV prevalence and incidence as measured by novel
assays; risk factors for incident HIV infection to detect new trends in the epidemic; HIV-related anemia;
appropriate transfusion therapy for HIV patients; and HIV lymphomas. The result of this program will be a
substantial improvement in human capital for HIV-related transfusion medicine and hematology research within
the two South African blood service organizations, UCT and neighboring southern African countries.
项目总结/文摘
项目成果
期刊论文数量(0)
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{{ truncateString('EDWARD L MURPHY', 18)}}的其他基金
Research training in HIV-related transfusion medicine and hematology in South Africa
南非艾滋病毒相关输血医学和血液学研究培训
- 批准号:
9977297 - 财政年份:2017
- 资助金额:
$ 7.3万 - 项目类别:
Blood Research and EnhAnced Training against HIV in South Africa (BREATH-SA)
南非艾滋病毒血液研究和强化培训 (BREATH-SA)
- 批准号:
10875043 - 财政年份:2017
- 资助金额:
$ 7.3万 - 项目类别:
XV International Conference on Human Retrovirology: HTLV and Related Viruses
第十五届人类逆转录病毒学国际会议:HTLV 及相关病毒
- 批准号:
8126612 - 财政年份:2011
- 资助金额:
$ 7.3万 - 项目类别:
Clinical Epidemiology of HTLV-I and HTLV-II Infection
HTLV-I 和 HTLV-II 感染的临床流行病学
- 批准号:
6704954 - 财政年份:2004
- 资助金额:
$ 7.3万 - 项目类别:
Clinical Epidemiology of HTLV-I and HTLV-II Infection
HTLV-I 和 HTLV-II 感染的临床流行病学
- 批准号:
7166834 - 财政年份:2004
- 资助金额:
$ 7.3万 - 项目类别:
Clinical Epidemiology of HTLV-I and HTLV-II Infection
HTLV-I 和 HTLV-II 感染的临床流行病学
- 批准号:
6841613 - 财政年份:2004
- 资助金额:
$ 7.3万 - 项目类别:
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