课题基金 / 基金详情

项目摘要

项目成果

JUAN ENRIQUE ROZENGURT的其他基金

相似基金

相关文献

中文摘要
翻译
描述(由申请人提供):第17届调节肽国际研讨会计划于2009年1月25日至28日在 费斯帕克的逸林度假村,圣巴巴拉,加州。肠道调节肽是一种结构上 在丰富的信息交换系统网络中发挥作用的不同分子信使群, 不仅在胃肠道(GI),而且在整个生物体中。监管的突出作用 胎儿/出生后发育中的肽,调节多种生理功能,包括脑/肠道 沟通和调节食物摄入,参与细胞修复/再生反应, 导致增殖性和炎性疾病的原因已经越来越明显。因此 这些肽的功能和治疗意义可以非常广泛。肠道调节肽 和神经肽,它们的受体和信号通路一直是深入研究的主题, 包括胃泌素释放肽(GRP)、促肾上腺皮质激素释放因子(CRF)、胆囊收缩素(CCK), 胃泌素、甘丙肽、GLP-1、GLP-2、GIP、胃饥饿素、胃动素、神经降压素、肽酪氨酸-酪氨酸(PYY), 速激肽和血管活性肠肽。人们对这些肽在不同的 学科,包括高度局部神经内分泌调节食物摄入的胃肠道 系统因此,迫切需要有一个中央论坛,比较和分享信息, 假设并为未来产生新的概念。调节肽国际研讨会 (REGPEP)汇集了领先的研究人员,介绍他们最近的发现,并讨论他们的数据, 该领域核心问题的背景。 这是一个两年一次的会议,有来自国际领先实验室的200多名研究人员参加 研究肠道调节肽的表达、受体信号传导和功能属性。一致 本着国际精神,会场在各大洲轮流举行,第一次研讨会是在 1976年在加州阿西洛马举行。本次研讨会的特点之一是维克多马特讲座 为表彰Viktor Mutt在胃肠道肽领域的基础研究而成立 激素和神经肽。自1994年以来,每两年在 调节肽国际研讨会。 会议的主要目标有三个:1)提供一个中心论坛, 新的和大部分未发表的信息,作为促进研究的手段; 2) 确定该领域的重要主题和技术进步,并为临床治疗制定目标; 3)吸引年轻的新研究人员到该领域来促进未来的研究。从以前的会议来看, 国际实验室之间的互动一直是刺激的,强大的和持久的;第17届国际 研讨会旨在继续进行信息和技术转让,以加速新的发展。
英文摘要
DESCRIPTION (provided by applicant): The 17th International Symposium on Regulatory Peptides is planned for January 25-28, 2009 at the Fess Parker's Doubletree Resort, Santa Barbara, California. Gut regulatory peptides are a structurally diverse group of molecular messengers that function in a rich network of information exchange systems not only in the gastrointestinal (GI) tract but also throughout the organism. The prominent roles of regulatory peptides in fetal/postnatal development, modulation of diverse physiological functions, including brain/gut communication and regulation of food intake, participation in cellular repair/regeneration responses and contributing to proliferative and inflammatory diseases have been increasingly evident. Accordingly, the functional and therapeutic significance of these peptides can be exceedingly broad. Gut regulatory peptides and neuropeptides, their receptors and signaling pathways have been the subject of intense investigation, including gastrin-releasing peptide (GRP), corticotropin-releasing factor (CRF), cholecystokinin (CCK), gastrin, galanin, GLP-1, GLP-2, GIP, ghrelin, motilin, neurotensin, peptide tyrosine-tyrosine (PYY), tachykinins and vasoactive intestinal peptide. There is extreme interest in these peptides in diverse disciplines, including the highly topical neuroendocrine regulation of food intake by the gastrointestinal system. Accordingly, there is an urgent need for a central forum to compare and share information, discuss hypotheses and generate new concepts for the future. The International Symposium on Regulatory Peptides (REGPEP) brings together leading investigators to present their recent findings and discuss their data in the context of central questions in the field. This is a biennial conference of more than 200 researchers from leading international laboratories studying the expression, receptor signaling and functional attributes of gut regulatory peptides. In keeping with the international spirit, the meeting sites have alternated on different continents; the first symposium was held in 1976 in Asilomar, California. One of the features of this Symposium is the Viktor Mutt Lectureship established in recognition of the fundamental research of Viktor Mutt in the field of gastrointestinal peptide hormones and neuropeptides. It has been awarded since 1994 every two years at the same time of the International Symposium on Regulatory Peptides. The major aims of the conference have been threefold: 1) to provide a central forum to disseminate new and largely unpublished information among investigators as a means of promoting research; 2) to identify important thematic and technological advancements in the field with goals for clinical therapeutics; and 3) to attract young new investigators to the field to foster future research. From previous meetings, the interactions among international laboratories have been stimulating, strong and durable; the 17th International Symposium aims to continue that information and technology transfer to accelerate new developments.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Project 2: Chemoprevention of pancreatic cancer with lipid-lowering and antidiabetic agents
Project 2: Chemoprevention of pancreatic cancer with lipid-lowering and antidiabetic agents
Identification of the growth-promoting PKD/YAP axis as a novel target for the statins in intestinal epithelial cells.
Identification of the growth-promoting PKD/YAP axis as a novel target for the statins in intestinal epithelial cells.
国内基金
海外基金
Sitagliptin通过microbiota-gut-brain轴在2型糖尿病致阿尔茨海默样变中的脑保护作用机制
  • 批准号:
    81801389
  • 项目类别:
    青年科学基金项目
  • 资助金额:
    21.0万元
  • 批准年份:
    2018
  • 负责人:
    田茗源
  • 依托单位:
平扫描数据导引的超低剂量Brain-PCT成像新方法研究
  • 批准号:
    81101046
  • 项目类别:
    青年科学基金项目
  • 资助金额:
    23.0万元
  • 批准年份:
    2011
  • 负责人:
    黄静
  • 依托单位: