Saliva and Salivary Gland Function Research Conference

描述(申请人提供)：此申请寻求支持2008年6月26-28日在纽约罗切斯特大学医学中心举行的唾液和唾液腺功能研究会议。这次会议将提供一个论坛，介绍和广泛讨论在理解唾液腺发育、功能和功能障碍的分子基础方面的最新进展。本次会议的总主题是腺组织的正常和疾病状态。个别会议将重点介绍关于以下方面的新见解：腺体形态发生和维持的分子和细胞相互作用；蛋白质、液体和电解质分泌；自身免疫性疾病(例如Sj‘gren综合征)及其治疗；细胞内信号及其空间组织；唾液作为诊断工具的使用；临床观察到的炎症和腺体功能障碍。主题演讲将以国际知名的研究人员为特色，他们涵盖组织工程和基因治疗应用领域的主题(Bruce J.Baum)，以及分泌性糖蛋白功能的探索(Lawrence A.Tabak)。 在组织这次会议时，确定了广泛的国际公认的发言者，包括有前途的初级和新成立的研究人员，他们的研究涉及或明显影响对唾液腺的发育和功能的理解。组织团队的目标是鼓励这一重要领域的发展和丰富，并鼓励研究唾液腺的新战略。 项目简介：本申请寻求对2008年6月26-28日在纽约罗切斯特大学医学中心举行的唾液和唾液腺功能研究会议的支持。这次会议将提供一个论坛，介绍和广泛讨论在理解唾液腺发育、功能和功能障碍的分子基础方面的最新进展。组织团队的目标是鼓励这一重要领域的发展和丰富，并鼓励研究唾液腺的新战略。

DESCRIPTION (provided by applicant): This application seeks support for a Research Conference on Saliva and Salivary Gland Function to be held June 26-28, 2008 at the University of Rochester Medical Center, New York. The conference will provide a forum for presentation and extensive discussion of the most recent progress in understanding the molecular basis of development, function and dysfunction of salivary glands. The general theme of this conference is normal and disease states of glandular tissues. Individual sessions will highlight new insights concerning molecular and cellular interactions underlying the glandular morphogenesis and maintenance; protein, fluid and electrolyte secretion; autoimmune diseases (e.g. Sj"gren's syndrome) and their treatment; intracellular signaling and its spatial organization; use of saliva as a diagnostic tool, and clinically observed inflammation and glandular dysfunction. Keynote addresses will feature established investigators of international stature who encompass themes in the areas of the application of tissue engineering and gene therapy (Bruce J. Baum), and in the exploration of secretory glycoprotein function (Lawrence A. Tabak). In organizing this conference, a broad range of internationally recognized speakers has been identified with the inclusion of promising junior and newly established investigators whose research either addresses or clearly impacts on the understanding of the development and function of salivary glands. It is the goal of the organizing team to encourage both growth and enrichment of this important field and to stimulate new strategies for studying salivary glands. Project Narrative: This application seeks support for a Research Conference on Saliva and Salivary Gland Function to be held June 26-28, 2008 at the University of Rochester Medical Center, New York. The conference will provide a forum for presentation and extensive discussion of the most recent progress in understanding the molecular basis of development, function and dysfunction of salivary glands. It is the goal of the organizing team to encourage both growth and enrichment of this important field and to stimulate new strategies for studying salivary glands.