2008 Spirochetes Gordon Research Conference

总结/摘要 第八届戈登螺旋体生物学研究会议将于 2008年1月至2月，加州文图拉。螺旋体生物学会议是 独特.这是目前唯一一次专门讨论基础研究的国际会议 所有医学上重要的和生物学上相关的螺旋体，一组独特的真细菌。 很多螺旋体都是病原体，它们能引起多种疾病，包括梅毒、莱姆病 疾病、回归热、钩端螺旋体病、牙周病、牛和猪的趾皮炎 和人类痢疾从历史上看，螺旋体一直很难研究。这些 细菌通常有苛刻的营养需求，许多还没有成功地 体外培养几种螺旋体的遗传操作和突变分析方法 物种不存在。为从事不同领域工作的团体提供交流意见的机会， 螺旋体一直是过去会议的最大好处之一，特别是在 基因操作的新技术和功能基因组学领域的扩展。的 疏螺旋体基因组序列的遗传进展和可用性的应用 burgdorferi、梅毒螺旋体（Treponema pallidum）、T.和钩端螺旋体属的新测序项目。 提供了大量的新信息结合起来，这些进步正在融入 正在进行的研究，生理学，结构，发病机制，和免疫生物学的这些 细菌 以前的每一次螺旋体生物学会议都非常成功， 受到与会者的高度赞扬，建立新的合作，提供一个论坛，介绍 对这些细菌的最新研究，并帮助确定新的研究方向。如在 鉴于前几次会议，我们预计2008年会议的出席人数将达到 150名教师，研究生，博士后研究员和工业科学家。广谱 代表不同研究兴趣、地理位置和资历的科学家将被 邀请出席。2008年，将作出特别努力，确保青年学生大量入学， 研究人员（研究生，博士后和初级教师），并实现公平 与会者的性别和种族分布。口头和海报介绍是 组织起来，提供许多讨论、交流思想的机会， 发展合作。请美国国立卫生研究院提供资金， 部分抵消了参与研究生的差旅费和注册费， 研究员和初级教员。

Summary/Abstract The eighth Gordon Research Conference on the Biology of Spirochetes will be held in January-February 2008 in Ventura, California. The Biology of Spirochetes Conference is unique. This is the only ongoing international meeting devoted to discussions on basic research of all medically important and biologically relevant spirochetes, a unique group of Eubacteria. Many spirochetes are pathogens, and they cause a variety of diseases, including syphilis, Lyme disease, relapsing fever, leptospirosis, periodontal disease, digital dermatitis of cattle, and swine and human dysentery. Historically, spirochetes have been very difficult to study. These bacteria often have fastidious nutritional requirements, and many have yet to be successfully cultured in vitro. Methods for genetic manipulation and mutational analysis of several spirochete species do not exist. The opportunity for exchange of ideas among groups working on different spirochetes has been one of the greatest benefits of past conferences, particularly in the area of new techniques for genetic manipulation and the expanding field of functional genomics. The application of genetic advancements and the availability of genomic sequences for Borrelia burgdorferi, Treponema pallidum, T. denticola, and new sequencing projects in Leptospira spp. are providing a wealth of new information. Combined, these advances are being integrated into ongoing studies on the physiology, structure, pathogenesis, and immunobiology of these bacteria. Each of the previous Biology of Spirochetes conferences has been highly successful, receiving high praise by attendees, forging new collaborations, providing a forum for presenting state-of-the-art research on these bacteria, and helping to set new research directions. As in previous conferences, we expect attendance at the 2008 conference to reach the maximum of 150 faculty, graduate students, postdoctoral fellows, and industrial scientists. A broad spectrum of scientists representing different research interests, geographic locations, and seniority will be invited to attend. For 2008, special efforts will be made to ensure strong attendance of young investigators (graduate students, post-docs, and junior faculty), and to achieve an equitable distribution in gender and ethnicity of attendees. The oral and poster presentations are organized to provide many opportunities for discussion, the exchange of ideas, and development of collaborations. Funding from the National Institutes of Health is requested to partially offset the travel and registration expenses of the participating graduate students, fellows, and junior faculty members.