CLINICAL TRIAL: ADULT AIDS CLINICAL TRIALS GROUP LONGITUDINAL LINKED RANDOMIZED

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 这项研究是为了了解人体对艾滋病毒感染的反应及其几年来的治疗。这项研究将考察的例子包括：1)什么药物组合在几年内效果最好；2)什么因素决定了帮助对抗感染和艾滋病毒的血细胞(T细胞)的数量；3)药物组合的给药顺序是否会影响结果；4)在长期(4年或更长时间)治疗艾滋病毒感染的过程中会出现什么样的副作用和疾病；5)有多少人经历过这些副作用和疾病；以及6)长期血液中病毒水平非常低或无法检测到的人(病毒载量)与病毒载量较高的人相比如何。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This study is being done to learn how the body responds to HIV infection and its treatment over several years. Examples of things the study will look at include: 1) What combinations of drugs work best over several years; 2) What factors determine the amount of blood cells (T cells) that help fight infection and HIV; 3) If the order in which combinations of drugs are given affects outcome; 4) What kinds of side effects and illnesses occur during long-term (4 or more years) treatment of HIV infection; 5) How many people experience these side effects and illnesses; and 6) How people with very low or undetectable levels of virus in their blood (viral load) for a long time compare with those whose viral load is higher.