Malaria Drug Resistance and Disease Virulence
Malaria Drug Resistance and Disease Virulence
批准号:
7592153
负责人:
Thomas E Wellems
金额:
$59.56万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至
关键词:
AntimalarialsAreaCellsDevelopmentDiagnosticDiagnostic testsDiseaseDisease ResistanceDrug resistanceGenesHumanInfectionInvestigationKnowledgeLaboratoriesMalariaModelingParasitesPharmaceutical PreparationsPlasmodium falciparumPrimatesProcessResearchResearch ActivityResearch Project GrantsResistanceTestingVaccinesVirulencechemotherapyfield studyimprovedmultidisciplinarynovel diagnosticsnovel therapeuticsprogramsresponsetool
中文摘要
这项研究项目的重点是疟疾寄生虫如何对主要抗疟疾药物产生抗药性,以及为什么最致命的疟疾寄生虫(恶性疟原虫)对人类和某些其他灵长类动物的细胞显示出不同的传染性。在这些领域中的每一个领域,我们都寻求研究进展,以提高对疟疾疾病过程的了解,从而支持新的抗疟疾化疗药物、诊断工具和疫苗的开发或测试。我们计划的研究活动是多学科的,包括对疟疾地区的实地考察以及基础实验室调查计划。
英文摘要
This research project focuses on how malaria parasites become resistant to major antimalarial drugs and why strains of the most deadly malaria parasite (Plasmodium falciparum) show different infectivities to cells of humans and certain other primates. In each of these areas we seek research advances that can improve the knowledge of disease processes in malaria and thereby support the development or testing of new antimalarial chemotherapies, diagnostic tools, and vaccines. The research activities in our program are multidisciplinary and include field studies in malarious regions as well as programs of basic laboratory investigation.
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专著(0)
科研奖励(0)
会议论文
Malaria Pathogenesis and Clinical Immunity
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批准号:7592351
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项目类别:
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资助金额:$68.07万
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财政年份:--
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负责人:Thomas E Wellems
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依托单位:
Malaria Drug Resistance and Disease Virulence
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批准号:8946267
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项目类别:
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资助金额:$121.33万
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财政年份:--
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负责人:Thomas E Wellems
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依托单位:
Biochemical And Biophysical Parasitology
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批准号:8946241
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项目类别:
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资助金额:$15.17万
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财政年份:--
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负责人:Thomas E Wellems
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依托单位:
Dry Season Ecology of Malaria Vectors
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批准号:10014227
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项目类别:
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资助金额:$52.16万
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财政年份:--
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负责人:Thomas E Wellems
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依托单位:
Drug Resistance, Antigenic Variation And Disease Severit
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批准号:7299938
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:Thomas E Wellems
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依托单位:
Drug Resistance/Antigenic Variation & Severity--Malaria
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批准号:7192852
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:Thomas E Wellems
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依托单位:
Dry Season Ecology of Malaria Vectors
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批准号:9161731
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项目类别:
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资助金额:$8.42万
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财政年份:--
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负责人:Thomas E Wellems
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依托单位:
Malaria Drug Resistance and Disease Virulence
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批准号:7964267
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项目类别:
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资助金额:$97.01万
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财政年份:--
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负责人:Thomas E Wellems
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依托单位:
Malaria Drug Resistance and Disease Virulence
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批准号:8745299
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项目类别:
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资助金额:$134.93万
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财政年份:--
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负责人:Thomas E Wellems
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依托单位:
Malaria Drug Resistance and Disease Virulence
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批准号:9161453
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项目类别:
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资助金额:$165.08万
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财政年份:--
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负责人:Thomas E Wellems
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依托单位:
Malaria Drug Resistance and Disease Virulence
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批准号:10692023
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项目类别:
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资助金额:$153.36万
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财政年份:--
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负责人:Thomas E Wellems
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依托单位:
Dry Season Ecology of Malaria Vectors
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批准号:9566762
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项目类别:
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资助金额:$25.3万
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财政年份:--
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负责人:Thomas E Wellems
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依托单位:
GENETICS OF DRUG RESISTANCE, ANTIGENIC VARIATION AND DIS
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批准号:6503186
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:Thomas E Wellems
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依托单位:
Genetics Of Drug Resistance, Antigenic Variation And Dis
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批准号:6669476
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:Thomas E Wellems
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依托单位:
Malaria Drug Resistance and Disease Virulence
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批准号:8156841
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项目类别:
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资助金额:$87.48万
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财政年份:--
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负责人:Thomas E Wellems
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依托单位:
Malaria Drug Resistance and Disease Virulence
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批准号:9354707
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项目类别:
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资助金额:$140.26万
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财政年份:--
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负责人:Thomas E Wellems
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依托单位:
Malaria Drug Resistance and Disease Virulence
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批准号:8555762
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项目类别:
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资助金额:$108.04万
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财政年份:--
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负责人:Thomas E Wellems
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依托单位:
Drug Resistance, Antigenic Variation & Malaria Severity
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批准号:6985596
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:Thomas E Wellems
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依托单位:
GENETICS OF DRUG RESISTANCE AND PATHOGENIC MECHANISMS IN P FALCIPARUM MALARIA
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批准号:6098943
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:Thomas E Wellems
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依托单位:
Malaria Drug Resistance and Disease Virulence
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批准号:10014028
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项目类别:
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资助金额:$134.13万
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财政年份:--
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负责人:Thomas E Wellems
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依托单位:
国内基金
海外基金
层出镰刀菌氮代谢调控因子AreA 介导伏马菌素 FB1 生物合成的作用机理
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批准号:2021JJ40433
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项目类别:省市级项目
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资助金额:--
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批准年份:2021
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负责人:孙磊
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依托单位:
寄主诱导梢腐病菌AreA和CYP51基因沉默增强甘蔗抗病性机制解析
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批准号:32001603
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项目类别:青年科学基金项目
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资助金额:24.0万元
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批准年份:2020
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负责人:段真珍
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依托单位:
AREA国际经济模型的移植.改进和应用
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批准号:18870435
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项目类别:面上项目
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资助金额:2.0万元
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批准年份:1988
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负责人:史树中
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依托单位: