IMPROVING THE CLINICAL APPLICABILITY OF PATHOPHYSIOLOGICAL MODELLING OF HYPOXAEMIA USING ROBUSTNESS ANALYSIS

本次研究合作将探索利用先进控制理论中的鲁棒性分析方法来开发、验证和改进生理仿真模型。特别是，申请人将专注于开发用于理解和管理低氧血症和呼吸暂停的改进模型，这些模型可以在具有代表性的患者群体中进行验证，从而显着提高其临床适用性。

The proposed research collaboration will explore the use of robustness analysis methods from advanced control theory for the development, validation and improvement of physiological simulation models. In particular, the applicants will focus on the development of improved models for understanding and managing hypoxaemia and apnoea, which can be validated across representative patient populations, thus significantly enhancing their clinical applicability.