Duke Training Grant in Digestive Diseases and Nutrition

描述(由申请人提供)： 该培训计划的目标是培养一批精选的医学博士和博士研究人员，从事学术胃肠病学基础和临床研究。完成这一计划后，学员将有资格担任医学院教师职位，进行独立的调查计划，并教学和参与临床活动。该计划的研究方向强调与细胞、器官和消化疾病与营养综合机制研究相关的生理学、细胞生物学和分子生物学技术。研究结果为胃肠道疾病临床治疗的学术发展提供了依据。 在过去15年的NIH培训资助下，我们已经培训了超过25名博士后和博士后候选人。这些人中超过70%的人已经进入学术职位，其中许多人得到了校外补助金的支持。自上次申请以来，我们已经修改了培训教员，删除了几名不是GL分区教员的培训师，并增加了来自GL分区的新培训师和助理培训师。培训人员都是美国国立卫生研究院、退伍军人管理局和/或行业资助的临床和基础研究人员。我们要求每年支持四名学员，理由是培训机会扩大、培训计划总体成功以及合格申请者的数量。我们将继续招聘合格的博士和代表人数不足的少数族裔候选人。 基本培训计划包括在一名或多名教员调查人员的直接监督下，以实验室为导向的密集研究经验。除此之外，还有通过研究生院、研讨会和期刊俱乐部进行的正式课程工作。此外，通过参加由杜克大学医学中心和达勒姆退伍军人事务医学中心胃肠病学部成员提供的大型住院、门诊和外展咨询服务，提供胃肠病学临床培训。临床研究培训包括正规课程工作和实际动手培训。该项目鼓励个人获得健康科学硕士学位。这些培训目标的实现将有助于培养能够在临床和基础方面进行高水平研究的内科科学家

DESCRIPTION (provided by applicant): The objective of this training program is to develop a selected group of M.D. and Ph.D. investigators for careers in basic and clinical research in academic gastroenterology. Upon completion of this program, trainees will be qualified to assume medical school faculty positions, conduct independent programs of investigation, and teach and participate in clinical activities. The research orientation of the program emphasizes techniques in physiology, cell biology and molecular biology relevant to the study of cell, organ and integrated mechanisms of digestive disease and nutrition. In outcomes provide a basis of academic development in clinical treatments of gastrointestinal disease. With previous NIH training grant support over the past 15 years we have trained over 25 pre- and post-doctoral candidates. Over seventy percent of these individuals have gone on to academic positions and many of these have extramural grant support. Since the last application, we have revised the training faculty, removing several trainers that were not Gl Divisional faculty and adding new trainers and associate trainers from the Gl Division. The training faculty are all NIH, VA and/or industry-funded investigators in clinical and basic research. We request support for four trainees per year, justified by the expanded training opportunities, the overall success of the training program and the number of qualified applicants. We shall continue to recruit qualified Ph.D. and under represented minority candidates. The basic training program consists of an intensive laboratory-oriented research experience under the direct supervision of one or more faculty investigators. This is supplemented with formal course work through the graduate school, seminars, and journal clubs. In addition, clinical training in gastroenterology is provided by participation in large inpatient, outpatient and outreach consult services staffed by members of the Division of Gastroenterology at Duke University Medical Center and Durham Veterans Affairs Medical Center. Training in clinical research involves formal course work and practical hands-on training. Individuals in this program are encouraged to obtain a Master's Degree in Health Sciences. Fulfillment of these training goals will serve to develop physician-scientists who can conduct high caliber research in both clinical and basic