Prefaculty Training in Pediatric Nephrology

描述(由申请人提供)： 这份申请是为了续订1965年在明尼苏达大学正式设立的儿科肾病学教职前培训计划。该项目的目的是为儿科肾科医生的学术生涯做准备。每年从已完成儿科或儿科/医学住院医师资格的候选人中挑选1-3名博士后实习生。培训时间为3年或以上。受训者至少有80%的时间在严密的教员监督下投入到研究中。该学院由11名儿科肾科医生组成，他们都积极从事研究。其中六人是美国国立卫生研究院拨款的首席调查人员。该小组的研究兴趣广泛，包括肾脏发育、肾细胞-基质相互作用、糖尿病肾病、高血压和儿童终末期肾病的流行病学、肾移植后的药物粘连、Alport综合征和肾小球足细胞病理生物学。实验室配备了分子生物学、电子显微镜、免疫组织化学、形态计量学、细胞和器官培养、肾脏疾病和肾脏发育的动物模型、流行病学和临床数据库管理等方面的研究，并配备了参与培训研究员执行实验室程序的科学家和技术人员。受训者要学习摘要的准备和演示，以及手稿和助学金的写作。该计划提供许多研究会议和说教讲座，并获得临床研究的科学硕士学位计划。与整个医学院的基础科学实验室有广泛的互动机会。我们的3名现任研究员和2名即将上任的研究员是女性。自1994年以来，该项目已有7名研究员毕业。所有的儿科肾脏病都是全职执业，6人有全职教职，2人有国家资助，2人有地方资助。该方案仍然坚定地致力于培养全国仍然短缺的儿科肾科学术医生，并帮助妇女和少数民族为这些职位做好准备。

DESCRIPTION (provided by applicant): This application is for renewal of the Prefaculty Training in Pediatric Nephrology program, formally established at the University of Minnesota (U of MN) in 1965. The program's aim is to prepare pediatric nephrologists for academic careers. 1- 3 post-doctoral trainees are selected annually from a pool of candidates who have completed residency in Pediatrics or Pediatrics/Medicine. Training is for 3 or more years. At least 80% of the trainees time is devoted to research under close faculty supervision. The faculty consists of 11 pediatric nephrologists who are all actively engaged in research. Six are principal investigators of NIH grants. Research interests of the group are broad, including renal development, renal cell-matrix interactions, diabetic nephropathy, epidemiology of hypertension and childhood ESRD, drug adherence after renal transplantation, Alport syndrome and glomerular podocyte pathobiology. Laboratories are equipped for studies in molecular biology, electron microscopy, immunohistochemistry, morphometry, cell and organ culture, animal models of renal disease and renal development, epidemiology, and clinical data base management, and are staffed by scientists and technicians who participate in training fellows to perform laboratory procedures. Trainees are schooled in abstract preparation and presentation, and manuscript and grant writing. The program offers numerous research conferences and didactic lectures, and access to the Master of Science Degree Program in Clinical Research. There is a wide range of opportunities for interaction with basic science laboratories throughout the Medical School. Our 3 current fellows and 2 incoming fellows are women. The program has graduated 7 fellows since 1994. All practice Pediatric Nephrology full time, 6 have full time academic faculty appointments, 2 have national funding and 2 have local funding. The program remains deeply committed to the development of academic pediatric nephrologists, who continue to be in short supply throughout the nation, and to the preparation of women and minorities for these positions